The Study of Nrf2 Signaling Pathway in Ovarian Cancer

被引：11
|
作者：
Wu, Xiaotong [1 ]
Han, Li Ying [1 ]
Zhang, Xiao Xiao [1 ]
Wang, Ling [1 ]
机构：
[1] Jilin Univ, Hosp 2, Dept Obstet & Gynecol, Changchun 130041, Jilin, Peoples R China
来源：
CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION | 2018年 / 28卷 / 04期
关键词：
ovarian cancer; oxidative stress; Nrf2; LOW-GRADE; CELL-MIGRATION; KEAP1; MUTATIONS; EXPRESSION; RESISTANCE; STRESS; RECOGNITION; SUPERFAMILY; INDUCTION;
D O I：
10.1615/CritRevEukaryotGeneExpr.2018020286
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Ovarian cancer is one of the most malignant gynecological tumors in the world, with a high fatality rate and resistance to chemotherapy. Much basic research has revealed that oxidative stress is involved in tumor occurrence and development processes and is associated with tumor progression as well as metastasis. In recent years, oxidative stress has been proven to have a close connection with malignant biological behavior in ovarian cancer, and this topic has garnered increasing attention. This article reviews the research aimed toward elucidating the relationship between oxidative stress and ovarian cancer.
引用
收藏
页码：329 / 336
页数：8
相关论文
共 50 条
  • [21] Therapeutic potentials of cannabidiol: Focus on the Nrf2 signaling pathway
    Talebi, Marjan
    Sadoughi, Mohammad Mehdi
    Ayatollahi, Seyed Abdulmajid
    Ainy, Elaheh
    Kiani, Roghayeh
    Zali, Alireza
    Miri, Mirmohammad
    [J]. BIOMEDICINE & PHARMACOTHERAPY, 2023, 168
  • [22] An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation
    Saha, Sarmistha
    Buttari, Brigitta
    Panieri, Emiliano
    Profumo, Elisabetta
    Saso, Luciano
    [J]. MOLECULES, 2020, 25 (22):
  • [23] The therapeutic effect of resveratrol: Focusing on the Nrf2 signaling pathway
    Farkhondeh, Tahereh
    Folgado, Silvia Llorens
    Pourbagher-Shahri, Ali Mohammad
    Ashrafizadeh, Milad
    Samarghandian, Saeed
    [J]. BIOMEDICINE & PHARMACOTHERAPY, 2020, 127
  • [24] Nrf2 signaling pathway in skin keratinocytes treated with cannabidiol
    Atalay, S.
    Gegotek, A.
    Jastrzab, A.
    Skrzydlewska, E.
    [J]. FEBS OPEN BIO, 2019, 9 : 133 - 133
  • [25] Natural Products as Modulators of Nrf2 Signaling Pathway in Neuroprotection
    Moratilla-Rivera, Ignacio
    Sanchez, Marta
    Valdes-Gonzalez, Jose Antonio
    Gomez-Serranillos, Maria Pilar
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (04)
  • [26] Role of the NRF2 signaling pathway in sustaining chemoresistance in medulloblastoma
    Rruga, Fatlum
    Mariotto, Elena
    Persano, Luca
    Rampazzo, Elena
    Luchini, Alessandra
    Liotta, Lance A.
    Viola, Giampietro
    Bortolozzi, Roberta
    [J]. MOLECULAR CANCER THERAPEUTICS, 2019, 18 (12)
  • [27] Anti-Osteoarthritis Mechanism of the Nrf2 Signaling Pathway
    Saha, Sarmistha
    Rebouh, Nazih Y.
    [J]. BIOMEDICINES, 2023, 11 (12)
  • [28] The KEAP1/NRF2 Signaling Pathway in Keratinization
    Ishitsuka, Yosuke
    Ogawa, Tatsuya
    Roop, Dennis
    [J]. ANTIOXIDANTS, 2020, 9 (08) : 1 - 24
  • [29] Proanthocyanidins Activate Nrf2/ARE Signaling Pathway in Intestinal Epithelial Cells by Inhibiting the Ubiquitinated Degradation of Nrf2
    Shuhua, Yang
    Lingqi, Meng
    Yunlong, Dang
    He, Tang
    Yao, Shi
    Peng, Li
    [J]. BIOMED RESEARCH INTERNATIONAL, 2022, 2022
  • [30] Coordination of ER and oxidative stress signaling: The PERK/Nrf2 signaling pathway
    Cullinan, SB
    Diehl, JA
    [J]. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2006, 38 (03): : 317 - 332
12345