The Study of Nrf2 Signaling Pathway in Ovarian Cancer

被引：11
|
作者：
Wu, Xiaotong [1 ]
Han, Li Ying [1 ]
Zhang, Xiao Xiao [1 ]
Wang, Ling [1 ]
机构：
[1] Jilin Univ, Hosp 2, Dept Obstet & Gynecol, Changchun 130041, Jilin, Peoples R China
来源：
CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION | 2018年 / 28卷 / 04期
关键词：
ovarian cancer; oxidative stress; Nrf2; LOW-GRADE; CELL-MIGRATION; KEAP1; MUTATIONS; EXPRESSION; RESISTANCE; STRESS; RECOGNITION; SUPERFAMILY; INDUCTION;
D O I：
10.1615/CritRevEukaryotGeneExpr.2018020286
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Ovarian cancer is one of the most malignant gynecological tumors in the world, with a high fatality rate and resistance to chemotherapy. Much basic research has revealed that oxidative stress is involved in tumor occurrence and development processes and is associated with tumor progression as well as metastasis. In recent years, oxidative stress has been proven to have a close connection with malignant biological behavior in ovarian cancer, and this topic has garnered increasing attention. This article reviews the research aimed toward elucidating the relationship between oxidative stress and ovarian cancer.
引用
收藏
页码：329 / 336
页数：8
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