Vesicular Stomatitis Virus-Based Vaccines against Lassa and Ebola Viruses

被引：137
|
作者：
Marzi, Andrea [1 ]
Feldmann, Friederike [1 ]
Geisbert, Thomas W. [2 ]
Feldmann, Heinz [1 ]
Safronetz, David [1 ]
机构：
[1] NIH, Hamilton, MT 59840 USA
[2] Univ Texas Med Branch, Galveston, TX 77555 USA
来源：
EMERGING INFECTIOUS DISEASES | 2015年 / 21卷 / 02期
基金：
美国国家卫生研究院;
关键词：
PROTECTS NONHUMAN-PRIMATES; ANTIBODIES; GLYCOPROTEINS; CHALLENGE; DISEASE;
D O I：
10.3201/eid2102.141649
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We demonstrated that previous vaccination with a vesicular stomatitis virus (VSV) based Lassa virus vaccine does not alter protective efficacy of subsequent vaccination with a VSV-based Ebola virus vaccine. These findings demonstrate the utility of VSV-based vaccines against divergent viral pathogens, even when preexisting immunity to the vaccine vector is present.
引用
收藏
页码：305 / 307
页数：3
相关论文
共 50 条
  • [21] Vesicular Stomatitis Virus-Based Vaccine Protects Mice against Crimean-Congo Hemorrhagic Fever
    Sergio E. Rodriguez
    Robert W. Cross
    Karla A. Fenton
    Dennis A. Bente
    Chad E. Mire
    Thomas W. Geisbert
    Scientific Reports, 9
  • [22] Individual and bivalent vaccines based on alphavirus replicons protect guinea pigs against infection with Lassa and Ebola viruses
    Pushko, P
    Geisbert, J
    Parker, M
    Jahrling, P
    Smith, J
    JOURNAL OF VIROLOGY, 2001, 75 (23) : 11677 - 11685
  • [23] Vesicular Stomatitis Virus-Based Vaccine Protects Mice against Crimean-Congo Hemorrhagic Fever
    Rodriguez, Sergio E.
    Cross, Robert W.
    Fenton, Karla A.
    Bente, Dennis A.
    Mire, Chad E.
    Geisbert, Thomas W.
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [24] A Recombinant Vesicular Stomatitis Virus-Based Vaccine Provides Postexposure Protection Against Bundibugyo Ebolavirus Infection
    Woolsey, Courtney
    Strampe, Jamie
    Fenton, Karla A.
    Agans, Krystle N.
    Martinez, Jasmine
    Borisevich, Viktoriya
    Dobias, Natalie S.
    Deer, Daniel J.
    Geisbert, Joan B.
    Cross, Robert W.
    Connor, John H.
    Geisbert, Thomas W.
    JOURNAL OF INFECTIOUS DISEASES, 2023, 228 : S712 - S720
  • [25] Hydrodynamic characterization of a vesicular stomatitis virus-based oncolytic virus using analytical ultracentrifugation
    Simon Wawra
    Sophia Kessler
    Arina Egel
    Johannes Solzin
    Oliver Burkert
    Daniel Hochdorfer
    European Biophysics Journal, 2023, 52 : 379 - 386
  • [26] Hydrodynamic characterization of a vesicular stomatitis virus-based oncolytic virus using analytical ultracentrifugation
    Wawra, Simon
    Kessler, Sophia
    Egel, Arina
    Solzin, Johannes
    Burkert, Oliver
    Hochdorfer, Daniel
    EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2023, 52 (4-5): : 379 - 386
  • [27] A Vesicular Stomatitis Virus-Based Hepatitis B Virus Vaccine Vector Provides Protection against Challenge in a Single Dose
    Cobleigh, Melissa A.
    Buonocore, Linda
    Uprichard, Susan L.
    Rose, John K.
    Robek, Michael D.
    JOURNAL OF VIROLOGY, 2010, 84 (15) : 7513 - 7522
  • [28] Vesicular stomatitis virus (VSV) as a paradigm for predicting antiviral activity against Ebola virus (EBOV)
    De Clercq, Erik
    MARMARA PHARMACEUTICAL JOURNAL, 2015, 19 (02) : 141 - 152
  • [29] Vesicular Stomatitis Virus Pseudotyped with Ebola Virus Glycoprotein Serves as a Protective, Noninfectious Vaccine against Ebola Virus Challenge in Mice
    Lennemann, Nicholas J.
    Herbert, Andrew S.
    Brouillette, Rachel
    Rhein, Bethany
    Bakken, Russell A.
    Perschbacher, Katherine J.
    Cooney, Ashley L.
    Miller-Hunt, Catherine L.
    Ten Eyck, Patrick
    Biggins, Julia
    Olinger, Gene
    Dye, John M.
    Maury, Wendy
    JOURNAL OF VIROLOGY, 2017, 91 (17)
  • [30] Vesicular Stomatitis Virus -based vaccines elicit strong immune response against Plasmodium falciparum
    Cheng, Y.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 1207 - 1207
12345