Clinical pharmacokinetics and interaction of centchroman - A mini review

被引：47
|
作者：
Lal, Jawahar [1 ]
机构：
[1] Cent Drug Res Inst, CSIR, Pharmacokinet & Metab Div, Lucknow 226001, Uttar Pradesh, India
来源：
CONTRACEPTION | 2010年 / 81卷 / 04期
关键词：
Centchroman; Ormeloxifene; Selective estrogen receptor modulator; Pharmacokinetics; Drug drug interaction; ENDOMETRIAL SENSITIVITY; TRIPHENYLETHYLENE ANTIESTROGEN; PINOPOD DEVELOPMENT; NIDATORY ESTROGEN; PLASMA-PROTEINS; RHESUS-MONKEY; BREAST-MILK; FEMALE RATS; HUMAN-SERUM; BINDING;
D O I：
10.1016/j.contraception.2009.11.007
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
This article provides a brief review of the information available regarding the published pharmacokinetics data for the nonsteroidal, once-a-week oral contraceptive, centchroman (INN: ormeloxifene). This agent is a unique need-oriented contraceptive agent which is included in the National Family Welfare Programme of India. Since 1991, centchroman has been used as a need-oriented contraceptive and is being given for treating dysfunctional bleeding of the uterus. Information regarding absorption, tissue distribution, elimination and kinetic interactions is discussed. (C) 2010 Elsevier Inc. All rights reserved.
引用
收藏
页码：275 / 280
页数：6
相关论文
共 50 条
  • [21] PHARMACOKINETICS OF CENTCHROMAN IN HEALTHY FEMALE SUBJECTS AFTER ORAL-ADMINISTRATION
    LAL, J
    ASTHANA, OP
    NITYANAND, S
    GUPTA, RC
    [J]. CONTRACEPTION, 1995, 52 (05) : 297 - 300
  • [22] Omadacycline: A Review of the Clinical Pharmacokinetics and Pharmacodynamics
    Rodvold, Keith A.
    Burgos, Rodrigo M.
    Tan, Xing
    Pai, Manjunath P.
    [J]. CLINICAL PHARMACOKINETICS, 2020, 59 (04) : 409 - 425
  • [23] Clinical Pharmacokinetics of Metoprolol: A Systematic Review
    Zamir, Ammara
    Hussain, Iltaf
    Rehman, Anees Ur
    Ashraf, Waseem
    Imran, Imran
    Saeed, Hamid
    Majeed, Abdul
    Alqahtani, Faleh
    Rasool, Muhammad Fawad
    [J]. CLINICAL PHARMACOKINETICS, 2022, 61 (08) : 1095 - 1114
  • [24] Daclatasvir: A Review of Preclinical and Clinical Pharmacokinetics
    Yash Gandhi
    Timothy Eley
    Aberra Fura
    Wenying Li
    Richard J. Bertz
    Tushar Garimella
    [J]. Clinical Pharmacokinetics, 2018, 57 : 911 - 928
  • [25] Clinical pharmacokinetics of cefixime: a systematic review
    Ajmal, Maria
    Zamir, Ammara
    Rehman, Anees ur
    Imran, Imran
    Saeed, Hamid
    Majeed, Abdul
    Aziz, Majid
    Alqahtani, Faleh
    Rasool, Muhammad Fawad
    [J]. XENOBIOTICA, 2023, 53 (03) : 149 - 162
  • [26] Clinical pharmacokinetics of vancomycin in the neonate: a review
    Pacifici, Gian Maria
    Allegaert, Karel
    [J]. CLINICS, 2012, 67 (07) : 831 - 837
  • [27] Clinical pharmacokinetics of nadolol: A systematic review
    Kalsoom, Samia
    Zamir, Ammara
    Rehman, Anees Ur
    Ashraf, Waseem
    Imran, Imran
    Saeed, Hamid
    Majeed, Abdul
    Alqahtani, Faleh
    Rasool, Muhammad Fawad
    [J]. JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2022, 47 (10) : 1506 - 1516
  • [28] Daclatasvir: A Review of Preclinical and Clinical Pharmacokinetics
    Gandhi, Yash
    Eley, Timothy
    Fura, Aberra
    Li, Wenying
    Bertz, Richard J.
    Garimella, Tushar
    [J]. CLINICAL PHARMACOKINETICS, 2018, 57 (08) : 911 - 928
  • [29] Clinical pharmacokinetics of melatonin: a systematic review
    Nathja Groth Harpsøe
    Lars Peter Holst Andersen
    Ismail Gögenur
    Jacob Rosenberg
    [J]. European Journal of Clinical Pharmacology, 2015, 71 : 901 - 909
  • [30] Pharmacokinetics of antimicrobials and their clinical implication - A review
    Dumka, VK
    Goyal, S
    Srivastava, AK
    [J]. INDIAN JOURNAL OF ANIMAL SCIENCES, 2005, 75 (06): : 691 - 699
12345