An improved method for the preparation of Ginsenoside Rg5 from ginseng fibrous root powder

被引：8
|
作者：
Guo, Dan-dan [1 ]
Cheng, Le-qin [1 ]
Zhang, Yue-wei [1 ]
Zheng, Hong-chao [2 ]
Ma, Hui-yong [3 ]
Li, Ling [4 ]
机构：
[1] Jilin Inst Chem Technol, Coll Chem & Pharmaceut Engn, Jilin 132022, Jilin, Peoples R China
[2] NIDDK, 31 Ctr Dr, Bethesda, MD 20892 USA
[3] Herbalife, 20481 Crescent Bay Dr, Lake Forest, CA 92630 USA
[4] Tonghua Baiaojinsen Biotechnol Co Ltd, Tonghua 134000, Peoples R China
来源：
HELIYON | 2019年 / 5卷 / 10期
关键词：
Natural product chemistry; Natural product synthesis; Hydrochloric acid; Ginsenoside-Rg5; Extraction; Ginseng fibrous root powder; Preparation; NATURAL-PRODUCTS; EXTRACTION; OPTIMIZATION; MARKET; RH3;
D O I：
10.1016/j.heliyon.2019.e02694
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Ginsenoside-Rg5, which is derived from high temperature-processed ginseng, exhibits beneficial health effects. In the present study, ginsenoside-Rg5 was directly and rapidly prepared through the extraction of ginseng fibrous root powder (GFRP) at atmospheric pressure. The results showed that the highest extraction yield (3.79%) was obtained under optimal conditions (extraction temperature of 85 degrees C, acid concentration of 0.06 mol/L, sample to solvent ratio of 1:55 g/mL and ethanol concentration of 95% after 4 h). The current method integrates the extraction of original saponins and the modification of the saponins to rare ginsenosides Rg5, which was more simpler operation, more milder preparation condition and more efficient.
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页数：6
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