An outbreak of highly pathogenic H5N1 avian influenza in Korea, 2008

被引：45

作者：

Kim, Hye-Ryoung ^{[1
]}

Park, Choi-Kyu ^{[1
]}

Lee, Youn-Jeong ^{[1
]}

Woo, Gye-Hyeong ^{[1
]}

Lee, Kyoung-Ki ^{[1
]}

Oem, Jae-Ku ^{[1
]}

Kim, Seong-Hee ^{[1
]}

Jean, Young-Hwa ^{[1
]}

Bae, Yu-Chan ^{[1
]}

Yoon, Soon-Seek ^{[1
]}

Roh, In-Soon ^{[1
]}

Jeong, Ok-Mi ^{[1
]}

Kim, Ha-Young ^{[1
]}

Choi, Jeong-Soo ^{[1
]}

Byun, Jae-Won ^{[1
]}

Song, Yun-Kyung ^{[1
]}

Kwon, Jun-Hun ^{[1
]}

Joo, Yi-Seok ^{[1
]}

机构：

[1] NVRQS, Gyeonggido 430824, South Korea

来源：

VETERINARY MICROBIOLOGY | 2010年 / 141卷 / 3-4期

关键词：

2; 3; Cade; HPAI; H5N1; Influenza A virus; A VIRUSES; MULTIPLE SUBLINEAGES; AMPLIFICATION; EVOLUTION; DUCKS; PCR;

D O I：

10.1016/j.vetmic.2009.09.011

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In spite of intensive surveillance programs for the control of HPAI, an outbreak of highly pathogenic avian influenza (HPAI) H5N1 in Korea in April 2008 caused serious damage to poultry farms, as did previous outbreaks in 2003/2004 and 2006/2007 Six viruses were selected from the Korean 2008 isolates for genetic analysis, and all eight gene segments from each of the influenza viruses were sequenced. A phylogenetic analysis showed that all of the viruses were of the same virus type and that the hemagglutinin (HA) gene was clustered with that of clade 2 3 2 viruses. However, the internal and neuraminidase (NA) genes were closely related to those of the clade 2.3.4 viruses (recent human and bird isolates from Southeast Asia). Crown Copyright (C) 2009 Published by Elsevier B.V. All rights reserved.

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页码：362 / 366

页数：5

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