Inflammatory Biomarkers and Atherosclerosis

被引：131
|
作者：
Soeki, Takeshi [1 ]
Sata, Masataka [1 ]
机构：
[1] Univ Tokushima, Grad Sch, Inst Biomed Sci, Dept Cardiovasc Med, 2-50-1 Kuramoto, Tokushima 7708503, Japan
来源：
INTERNATIONAL HEART JOURNAL | 2016年 / 57卷 / 02期
关键词：
Epicardial adipose tissue (EAT); Inflammation; MicroRNA (miRNA); Pentraxin 3 (PTX3); CORONARY-ARTERY-DISEASE; CIRCULATING MICRORNAS; CARDIOVASCULAR EVENTS; MYOCARDIAL-INFARCTION; PHOSPHOLIPASE A(2); HEART-DISEASE; FUTURE RISK; MYELOPEROXIDASE; PROTEIN; MARKER;
D O I：
10.1536/ihj.15-346
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Atherosclerosis has been regarded as a form of chronic vascular inflammation. Numerous biomarkers associated with inflammation have been identified as novel targets to monitor atherosclerosis and cardiovascular risk. C-reactive protein (CRP) is one of the most actively studied and established inflammatory biomarkers for cardiovascular events. However, CRP response is triggered by many disorders unrelated to cardiovascular disease, which interferes with the clinical application. This review describes established and traditional inflammatory biomarkers including CRP as well as novel inflammatory biomarkers reflective of local atherosclerotic inflammation. In addition, we focus on the potential usefulness of inflammatory biomarkers in developing anti-atherosclerotic therapeutic approaches.
引用
收藏
页码：134 / 139
页数：6
相关论文
共 50 条
  • [41] Biomarkers of atherosclerosis: Clinical applications
    Brown T.M.
    Bittner V.
    [J]. Current Cardiology Reports, 2008, 10 (6) : 497 - 504
  • [42] Biomarkers of atherosclerosis: Clinical applications
    Brown T.M.
    Bittner V.
    [J]. Current Cardiovascular Risk Reports, 2009, 3 (1) : 23 - 30
  • [43] Atherosclerosis is an inflammatory disease
    Fabrizio Montecucco
    François Mach
    [J]. Seminars in Immunopathology, 2009, 31 : 1 - 3
  • [44] Atherosclerosis in inflammatory diseases
    Kovanen, Petri
    [J]. SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, 2008, 37 : 6 - 6
  • [45] Inflammatory atherosclerosis in women
    Frink, RJ
    [J]. CIRCULATION, 2005, 111 (04) : E56 - E56
  • [46] Atherosclerosis is an inflammatory disease
    Ross, R
    [J]. AMERICAN HEART JOURNAL, 1999, 138 (05) : S419 - S420
  • [47] Inflammatory mechanisms in atherosclerosis
    Wolf, D.
    Stachon, P.
    Bode, C.
    Zirlik, A.
    [J]. HAMOSTASEOLOGIE, 2014, 34 (01): : 63 - 71
  • [48] ATHEROSCLEROSIS AS AN INFLAMMATORY DISEASE
    CAPRON, L
    [J]. REVUE DE MEDECINE INTERNE, 1988, 9 (04): : 359 - 361
  • [49] Atherosclerosis - An inflammatory disease
    Williams, KJ
    Tabas, I
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (24): : 1928 - 1928
  • [50] Atherosclerosis: an inflammatory disease
    Ait-Oufella, Hafid
    Tedgui, Alain
    Mallat, Ziad
    [J]. SANG THROMBOSE VAISSEAUX, 2008, 20 (01): : 25 - 33
12345