Inflammatory Biomarkers and Atherosclerosis

被引：131

作者：

Soeki, Takeshi ^{[1
]}

Sata, Masataka ^{[1
]}

机构：

[1] Univ Tokushima, Grad Sch, Inst Biomed Sci, Dept Cardiovasc Med, 2-50-1 Kuramoto, Tokushima 7708503, Japan

来源：

INTERNATIONAL HEART JOURNAL | 2016年 / 57卷 / 02期

关键词：

Epicardial adipose tissue (EAT); Inflammation; MicroRNA (miRNA); Pentraxin 3 (PTX3); CORONARY-ARTERY-DISEASE; CIRCULATING MICRORNAS; CARDIOVASCULAR EVENTS; MYOCARDIAL-INFARCTION; PHOSPHOLIPASE A(2); HEART-DISEASE; FUTURE RISK; MYELOPEROXIDASE; PROTEIN; MARKER;

D O I：

10.1536/ihj.15-346

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Atherosclerosis has been regarded as a form of chronic vascular inflammation. Numerous biomarkers associated with inflammation have been identified as novel targets to monitor atherosclerosis and cardiovascular risk. C-reactive protein (CRP) is one of the most actively studied and established inflammatory biomarkers for cardiovascular events. However, CRP response is triggered by many disorders unrelated to cardiovascular disease, which interferes with the clinical application. This review describes established and traditional inflammatory biomarkers including CRP as well as novel inflammatory biomarkers reflective of local atherosclerotic inflammation. In addition, we focus on the potential usefulness of inflammatory biomarkers in developing anti-atherosclerotic therapeutic approaches.

引用

页码：134 / 139

页数：6

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