The immunological synapse and actin assembly: A regulatory role for PKC0

被引：23
|
作者：
Thome, M [1 ]
机构：
[1] Univ Lausanne, Inst Biochem, CH-1066 Epalinges, Switzerland
来源：
DEVELOPMENTAL CELL | 2003年 / 4卷 / 01期
关键词：
D O I：
10.1016/S1534-5807(02)00407-0
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Engagement of the T cell receptor leads to the accumulation of filamentous actin, which is necessary for the formation of the immunological synapse and subsequent T cell activation. In the December issue of Molecular Cell, Sasahara et al. provide new insights into the link between the T cell receptor and actin assembly in the immunological synapse, and reveal a critical regulatory role for PKCtheta in this process.
引用
收藏
页码：3 / 5
页数：3
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