New cyclopeptide alkaloid and lignan glycoside from Justicia procumbens

被引：7
|
作者：
Jin, Hong [1 ]
Chen, Li [1 ]
Tian, Ying [1 ]
Li, Bin [1 ]
Dong, Jun-Xing [1 ]
机构：
[1] Beijing Inst Radiat Med, Beijing 100850, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2015年 / 17卷 / 01期
关键词：
Justicia procumbens; cyclopeptide alkaloid; lignan glycoside; cytotoxic; SCUTIA-BUXIFOLIA; CONSTITUENTS;
D O I：
10.1080/10286020.2014.968560
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
This study reported a new cyclopeptide alkaloid, justicianene A (1), and a new lignan glycoside, procumbenoside H (2), isolated from Justicia procumbens. The structures of the new compounds were elucidated by means of spectroscopic analysis, including extensive 2D NMR studies and mass spectrometry. Cyclopeptide alkaloids were first observed from the genus Justicia. Compound 2 was cytotoxic against human LoVo colon carcinoma cells with an IC50 value of 17.908 +/- 1.949 mu M.
引用
收藏
页码：33 / 39
页数：7
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