One-pot, two-step synthesis of substituted triazoloquinoxalinone starting from 3-hydrazineylquinoxalin-2(1H)-one

被引：3

作者：

Patil, Vikas S. ^{[1
]}

Yadavalli, Subba Rao ^{[1
]}

Merugu, Ramchander ^{[2
]}

Swamy, S. J. ^{[3
]}

Devunuri, Nagaraju ^{[1
]}

机构：

[1] Vignans Fdn Sci Technol & Res VFSTR Deemed Univ, Div Chem, Dept Sci & Humanities, Guntur 522213, Andhra Pradesh, India

[2] Mahatma Gandhi Univ, Dept Bio Chem, Nalgonda, India

[3] Kakatiya Univ, Dept Chem, Warangal, Andhra Pradesh, India

来源：

SYNTHETIC COMMUNICATIONS | 2021年 / 51卷 / 13期

关键词：

Hydrazine; ferric chloride; 3-hydrazineylquinoxalin-2(1H)-one; DERIVATIVES; MELANOMA; DESIGN;

D O I：

10.1080/00397911.2021.1918171

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient one-pot two-step synthesis of substituted-triazolo[4,3-a]quinoxalin-4(5H)-one has been developed. The 3-hydrazineylquinoxalin-2(1H)-one reacts with respective aldehyde to afford the individual hydrazineylidene intermediate which undergoes oxidative cyclization in the presence of ferric chloride hexahydrate (FeCl3.6H(2)O) to affords various substituted- triazolo[4,3-a]quinoxalin-4(5H)-one in good to excellent yields.

引用

页码：1994 / 2000

页数：7

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