MULTIFOCUS THERMAL STRAIN IMAGING USING A CURVED LINEAR ARRAY TRANSDUCER FOR IDENTIFICATION OF LIPIDS IN DEEP TISSUE

被引:1
|
作者
Khalid, Waqas B. [1 ]
Chen, Xucai [2 ,3 ]
Kim, Kang [1 ,2 ,3 ,4 ,5 ,6 ]
机构
[1] Univ Pittsburgh, Sch Engn, Dept Bioengn, Pittsburgh, PA 15261 USA
[2] Univ Pittsburgh, Sch Med, Dept Med, Pittsburgh, PA 15213 USA
[3] Univ Pittsburgh, Sch Med, Dept Med,Heart & Vasc Inst, Ctr Ultrasound Mol Imaging & Therapeut,Med Ctr, Pittsburgh, PA 15213 USA
[4] Univ Pittsburgh, Sch Engn, Dept Mech Engn & Mat Sci, Pittsburgh, PA 15261 USA
[5] Univ Pittsburgh, McGowan Inst Regenerat Med, Pittsburgh, PA USA
[6] Univ Pittsburgh, Med Ctr, Pittsburgh, PA USA
来源
ULTRASOUND IN MEDICINE AND BIOLOGY | 2021年 / 47卷 / 07期
关键词
Curved linear array transducer; Multifocus beamforming; Non-alcoholic fatty liver disease; Ultra-sound thermal strain imaging; FATTY LIVER-DISEASE; TEMPERATURE ESTIMATION; DIAGNOSTIC-ACCURACY; ULTRASOUND; PLAQUE; BIOPSY; IVUS; ASSOCIATION; CAVITATION; MODEL;
D O I
10.1016/j.ultrasmedbio.2021.03.005
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
Thermal strain imaging (TSI) is an ultrasound-based imaging technique intended primarily for diseases in which lipid accumulation is the main biomarker. The goal of the research described here was to successfully implement TSI on a single, commercially available curved linear array transducer for heating and imaging of organs at a deeper depth. For an effective temperature rise of the tissue over a large area, which is key to TSI performance, an innovative multifocus beamforming approach was applied. This yielded a heating area from 32 to 96 mm in the axial direction and - 7 to +7 mm in the lateral direction. The pressure fields generated from simulation were in agreement with pressure fields measured with the hydrophone. TSI with safe acoustic power identified with high contrast a rubber inclusion and liposuction fat tissue embedded in a gelatin block. (C) 2021 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
引用
收藏
页码:1711 / 1724
页数:14
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