Stem cell-derived β cells go in monkeys

被引：2

作者：

Grapin-Botton, Anne ^{[1
,2
,3
]}

Ludwig, Barbara ^{[2
,3
,4
,5
,6
]}

机构：

[1] Max Planck Inst Mol Cell Biol & Genet, D-01307 Dresden, Germany

[2] Tech Univ Dresden, Univ Hosp Carl Gustav Carus, Helmholtz Ctr Munich, Paul Langerhans Inst Dresden, D-01307 Dresden, Germany

[3] Tech Univ Dresden, Fac Med, D-01307 Dresden, Germany

[4] Tech Univ Dresden, Univ Hosp Carl Gustav Carus, Dept Med 3, D-01307 Dresden, Germany

[5] Ctr Diabet Res DZD eV, D-85764 Neuherberg, Germany

[6] Tech Univ Desden, DFG Ctr Regenerat Therapies Dresden, D-01307 Dresden, Germany

来源：

CELL STEM CELL | 2022年 / 29卷 / 04期

关键词：

D O I：

10.1016/j.stem.2022.03.010

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Du et al. transplanted 0 cells derived from pluripotent stem cells in diabetic monkeys for the first time, as an intermediate stage toward clinical translation. They observed benefits unfolding over months but also observed immune rejection of the grafts by 5-6 months.

引用

页码：500 / 502

页数：3

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