Adsorptive transfer stripping voltammetry applied to the study of the interaction between DNA and actinomycin

被引：4
|
作者：
Gherghi, IC
Girousi, ST [1 ]
Voulgaropoulos, A
Tzimou-Tsitouridou, R
机构：
[1] Aristotle Univ Thessaloniki, Dept Chem, Analyt Chem Lab, Thessaloniki 54124, Greece
[2] Aristotle Univ Thessaloniki, Dept Chem Engn, Thessaloniki 54124, Greece
来源：
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY | 2004年 / 84卷 / 11期
关键词：
actinomycin D; adsorptive transfer stripping voltammetry; DNA; CPE; intercalator; anti-cancer drugs;
D O I：
10.1080/03067310310001626722
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Actinomycin D is an antitumor antibiotic which intercalates within DNA. The interaction of actinomycin D with double-stranded and thermally denatured (single-stranded) calf thymus DNA was studied in solution as well as at the electrode surface using differential pulse transfer voltammetry with carbon paste electrode in 0.2 M acetate buffer, pH 5.0.
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页码：865 / 874
页数：10
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