Degradation of Microcystin-LR and RR by a Stenotrophomonas sp Strain EMS Isolated from Lake Taihu, China

被引：79
|
作者：
Chen, Jian [1 ,3 ]
Hu, Liang Bin [2 ]
Zhou, Wei [1 ,3 ]
Yan, Shao Hua [3 ,4 ]
Yang, Jing Dong [1 ,3 ]
Xue, Yan Feng [1 ,3 ]
Shi, Zhi Qi [1 ,3 ]
机构：
[1] Jiangsu Acad Agr Sci, Inst Food Safety & Qual, Nanjing 210014, Peoples R China
[2] Henan Inst Sci & Technol, Sch Food, Xinxiang 453003, Peoples R China
[3] Minist Agr, Key Lab Food Safety Monitoring & Management, Nanjing 210014, Peoples R China
[4] Jiangsu Acad Agr Sci, Inst Resources & Environm Sci, Nanjing 210014, Peoples R China
来源：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2010年 / 11卷 / 03期
基金：
中国国家自然科学基金;
关键词：
degradation; microcystin-LR; microcystin-RR; cyanobacteria; EMS; mlrA; BACTERIAL-DEGRADATION; CYANOBACTERIAL TOXIN; WATER; BIODEGRADATION; DNA; EUTROPHICATION; PEPTIDES; GROWTH;
D O I：
10.3390/ijms11030896
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A bacterial strain EMS with the capability of degrading microcystins (MCs) was isolated from Lake Taihu, China. The bacterium was tentatively identified as a Stenotrophomonas sp. The bacterium could completely consume MC-LR and MC-RR within 24 hours at a concentration of 0.7 mu g/mL and 1.7 mu g/mL, respectively. The degradation of MC-LR and MC-RR by EMS occurred preferentially in an alkaline environment. In addition, mlrA gene involved in the degradation of MC-LR and MC-RR was detected in EMS. Due to the limited literature this gene has rare homologues. Sequencing analysis of the translated protein from mlrA suggested that MlrA might be a transmembrane protein, which suggests a possible new protease family having unique function.
引用
收藏
页码：896 / 911
页数：16
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