Preclinical pharmacokinetics and biodistribution studies of 89Zr-labeled pembrolizumab for human dosimetry estimation

被引：0
|
作者：
Ehlerding, Emily [1 ]
England, Christopher [1 ]
Hernandez, Reinier [1 ]
Graves, Stephen [2 ]
Barnhart, Todd [1 ]
Cai, Weibo [1 ]
机构：
[1] Univ Wisconsin, Madison, WI USA
[2] Univ Wisconsin, Dept Med Phys, 1530 Med Sci Ctr, Madison, WI 53706 USA
来源：
JOURNAL OF NUCLEAR MEDICINE | 2016年 / 57卷
关键词：
D O I：
暂无
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
1023
引用
收藏
页数：2
相关论文
共 50 条
  • [31] Microfluidic Preparation of a 89Zr-Labeled Trastuzumab Single-Patient Dose
    Wright, Brian D.
    Whittenberg, Joseph
    Desai, Amit
    DiFelice, Christina
    Kenis, Paul J. A.
    Lapi, Suzanne E.
    Reichert, David E.
    JOURNAL OF NUCLEAR MEDICINE, 2016, 57 (05) : 747 - 752
  • [32] Site-Specific Photoaffinity Bioconjugation for the Creation of 89Zr-Labeled Radioimmunoconjugates
    Delaney, Samantha
    Nagy, Abel
    Karlstrom, Amelie Eriksson
    Zeglis, Brian M.
    MOLECULAR IMAGING AND BIOLOGY, 2023, 25 (6) : 1104 - 1114
  • [33] Influence of the conjugation strategy on the stability of 89Zr-labeled immunoconjugates towards radiolysis
    Vizier, Romane
    Adumeau, Pierre
    Goncalves, Victor
    Denat, Franck
    NUCLEAR MEDICINE AND BIOLOGY, 2022, 108 : S120 - S120
  • [34] 89Zr-labeled anti-PD-L1 Probody therapeutic CX-072 biodistribution in mice bearing human xenograft or murine syngeneic tumors
    Giesen, Danique
    Broer, Linda N.
    Lub-de Hooge, Marjolijn N.
    Popova, Irina
    Howng, Bruce
    Vasiljeva, Olga
    de Vries, Elisabeth G.
    Pool, Martin
    CANCER RESEARCH, 2018, 78 (13)
  • [35] An 89Zr-Labeled PSMA Tracer for PET/CT Imaging of Prostate Cancer Patients
    Dietlein, Felix
    Kobe, Carsten
    Vazquez, Sergio Munoz
    Fischer, Thomas
    Endepols, Heike
    Hohberg, Melanie
    Reifegerst, Manuel
    Neumaier, Bernd
    Schomaecker, Klaus
    Drzezga, Alexander E.
    Dietlein, Markus
    JOURNAL OF NUCLEAR MEDICINE, 2022, 63 (04) : 573 - 583
  • [36] In vitro and in vivo evaluation of a 89Zr-labeled anti-TIP1 antibody
    Boas, Cristian Wieczorek Villas
    Lewis, Calvin
    Signh, Abhay
    Hallahan, Dennis
    Kapoor, Vaishali
    Rogers, Buck
    NUCLEAR MEDICINE AND BIOLOGY, 2022, 108 : S37 - S38
  • [37] Quantitative Biodistribution and Pharmacokinetics Study of GMP-Grade Exosomes Labeled with 89Zr Radioisotope in Mice and Rats
    Choi, Hojun
    Kim, Myung-Yoon
    Kim, Dae-Hwan
    Yun, Hanoul
    Oh, Byung-Koo
    Kim, Su-Bin
    Song, In-Ho
    Park, Hyun-Soo
    Kim, Sang-Eun
    Park, Cheolhyoung
    Choi, Chulhee
    PHARMACEUTICS, 2022, 14 (06)
  • [38] PET Molecular Imaging of 89Zr-Labeled Monoclonal Antibodies - Solid Target System and Automatic Purification System for 89Zr-
    Kato, Jun
    Oda, Takashi
    Ueno, Satoshi
    Ishizuka, Toru
    Yano, Tsuneo
    JOURNAL OF NUCLEAR MEDICINE, 2015, 56 (03)
  • [39] Critical impact of the conjugation strategy on the stability of 89Zr-labeled immunoconjugates towards radiolysis
    Adumeau, P.
    Moreau, M.
    Da Costa, L.
    Bernhard, C.
    Dubois, A.
    Goncalves, V.
    Denat, F.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2019, 46 (SUPPL 1) : S727 - S727
  • [40] A radioactive CRISPR interference system using 89Zr-labeled LbCas12a
    Hwang, Injoo
    Lee, Jun Young
    Kim, Tae-Hyun
    Lee, Eun Ju
    Kim, Jeeho
    Park, Hyomin
    Hur, Min Goo
    Lee, Sanghwa
    Park, Jeong-Hoon
    JOURNAL OF CONTROLLED RELEASE, 2024, 365 : 703 - 715
12345