Liraglutide alleviates hepatic steatosis and liver injury in type 2 diabetes rats via a GLP-1R dependent AMPK pathway

被引：0
|
作者：
Yang, L. [1 ]
Lin, C. [1 ]
Zhou, R. [2 ]
Zhao, L. [2 ]
Zhuo, X. [1 ]
机构：
[1] Southern Med Univ, Dept Endocrinol, Zhujiang Hosp, Guangzhou, Guangdong, Peoples R China
[2] Southern Med Univ, Sch Basic Med Sci, Dept Pathol, Guangzhou, Guangdong, Peoples R China
来源：
DIABETOLOGIA | 2019年 / 62卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
635
引用
收藏
页码：S305 / S305
页数：1
相关论文
共 50 条
  • [31] Meta analysis of the efficacy of GLP-1R agonists and DPP-4 inhibitors for treatment of type 2 diabetes mellitus
    Aroda, V. R.
    Henry, R. R.
    Han, J.
    Huang, W.
    Peters, Y.
    Darsow, T.
    Hoogwerf, B. J.
    DIABETOLOGIA, 2010, 53
  • [32] Role of adipose tissue GLP-1R expression in metabolic improvement after bariatric surgery in patients with type 2 diabetes
    Ejarque, Miriam
    Guerrero-Perez, Fernando
    de la Morena, Nuria
    Casajoana, Anna
    Virgili, Nuria
    Lopez-Urdiales, Rafael
    Maymo-Masip, Elsa
    Pujol Gebelli, Jordi
    Ruiz de Gordejuela, Amador Garcia
    Perez-Maraver, Manuel
    Pellitero, Silvia
    Fernandez-Veledo, Sonia
    Vendrell, Joan
    Vilarrasa, Nuria
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [33] Risk Factors of Atherosclerosis and Immune Status of Monocytes Are Associated with Circulating Monocyte GLP-1R Levels in Type 2 Diabetes
    Motoyama, Koka
    Emoto, Masanori
    Mishima, Takashi
    Yamazaki, Yuko
    Morioka, Tomoaki
    Mori, Katsuhito
    Fukumoto, Shinya
    Shoji, Tetsuo
    Inaba, Masaaki
    DIABETES, 2014, 63 : A490 - A490
  • [34] Discovery of non-peptide GLP-1r natural agonists for enhancing coronary safety in type 2 diabetes patients
    Shakour, Neda
    Hoseinpoor, Saeideh
    Rajabian, Fatemeh
    Azimi, Sabikeh G.
    Iranshahi, Mehrdad
    Sadeghi-Aliabadi, Hojjat
    Hadizadeh, Farzin
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2025, 43 (07): : 3508 - 3525
  • [35] Role of adipose tissue GLP-1R expression in metabolic improvement after bariatric surgery in patients with type 2 diabetes
    Miriam Ejarque
    Fernando Guerrero-Pérez
    Nuria de la Morena
    Anna Casajoana
    Nuria Virgili
    Rafael López-Urdiales
    Elsa Maymó-Masip
    Jordi Pujol Gebelli
    Amador Garcia Ruiz de Gordejuela
    Manuel Perez-Maraver
    Silvia Pellitero
    Sonia Fernández-Veledo
    Joan Vendrell
    Nuria Vilarrasa
    Scientific Reports, 9
  • [36] Genetic Variation in GLP-1R Modify the Risk of Hypoglycemia in Response to Intensive Glycemic Control in Adults with Type 2 Diabetes
    Xue, Qiaochu
    Li, Piaopiao
    Jagannathan, Ram
    Pasquel, Francisco J.
    Umpierrez, Guillermo
    Phillips, Lawrence S.
    Ali, Mohammed K.
    Shao, Hui
    DIABETES, 2024, 73
  • [37] GLP-1R activation by exendin-4 prevents neuronal loss in the piriform cortex of type 2 diabetic rats
    Lietzau, G.
    Darsalia, V.
    Otstenson, C. -G.
    Nystrom, T.
    Patrone, C.
    DIABETOLOGIA, 2015, 58 : S72 - S72
  • [38] Fingolimod alleviates type 2 diabetes associated cognitive decline by regulating autophagy and neuronal apoptosis via AMPK/mTOR pathway
    Li, Jie
    Yin, Mingjie
    Wang, Zhen
    Xiong, Yifei
    Fang, Xuedi
    Fang, Hui
    BRAIN RESEARCH, 2025, 1846
  • [39] Exendin-4 attenuates neuronal death via GLP-1R/PI3K/Akt pathway in early brain injury after subarachnoid hemorrhage in rats
    Xie, Zhiyi
    Enkhjargal, Budbazar
    Wu, Lingyun
    Zhou, Keren
    Sun, Chengmei
    Hu, Xin
    Gospodarev, Vadim
    Tang, Jiping
    You, Chao
    Zhang, John H.
    NEUROPHARMACOLOGY, 2018, 128 : 142 - 151
  • [40] Alogliptin alleviates hepatic steatosis in a mouse model of nonalcoholic fatty liver disease by promoting CPT1a expression via Thr172 phosphorylation of AMPKα in the liver
    Tobita, Hiroshi
    Sato, Shuichi
    Yazaki, Tomotaka
    Mishiro, Tsuyoshi
    Ishimura, Norihisa
    Ishihara, Shunnji
    Kinoshita, Yoshikazu
    MOLECULAR MEDICINE REPORTS, 2018, 17 (05) : 6840 - 6846
12345