Liraglutide alleviates hepatic steatosis and liver injury in type 2 diabetes rats via a GLP-1R dependent AMPK pathway

被引：0
|
作者：
Yang, L. [1 ]
Lin, C. [1 ]
Zhou, R. [2 ]
Zhao, L. [2 ]
Zhuo, X. [1 ]
机构：
[1] Southern Med Univ, Dept Endocrinol, Zhujiang Hosp, Guangzhou, Guangdong, Peoples R China
[2] Southern Med Univ, Sch Basic Med Sci, Dept Pathol, Guangzhou, Guangdong, Peoples R China
来源：
DIABETOLOGIA | 2019年 / 62卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
635
引用
收藏
页码：S305 / S305
页数：1
相关论文
共 50 条
  • [1] Liraglutide Alleviates Hepatic Steatosis and Liver Injury in T2MD Rats via a GLP-1R Dependent AMPK Pathway
    Zhou, Rui
    Lin, Chuman
    Cheng, Yanzhen
    Zhuo, Xiaoyun
    Li, Qinghua
    Xu, Wen
    Zhao, Liang
    Yang, Li
    FRONTIERS IN PHARMACOLOGY, 2021, 11
  • [2] GLP-1R Agonists Therapy for Type 2 Diabetes
    ZHOU Bilan
    PENG Anlin
    GONG Hao
    HUANG Kun
    WuhanUniversityJournalofNaturalSciences, 2014, 19 (01) : 27 - 33
  • [3] GLP-1 regulates exercise endurance and skeletal muscle remodeling via GLP-1R/AMPK pathway
    Wu, Luting
    Zhou, Min
    Li, Tianyou
    Dong, Niu
    Yi, Long
    Zhang, Qianyong
    Mi, Mantian
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2022, 1869 (09):
  • [4] Liraglutide activates autophagy via GLP-1R to improve functional recovery after spinal cord injury
    Chen, Jian
    Wang, Zhouguang
    Mao, Yuqin
    Zheng, Zengming
    Chen, Yu
    Khor, Sinan
    Shi, Kesi
    He, Zili
    Li, Jiawei
    Gong, Fanghua
    Liu, Yanlong
    Hu, Aiping
    Xiao, Jian
    Wang, Xiangyang
    ONCOTARGET, 2017, 8 (49) : 85949 - 85968
  • [5] ROLE OF GLP-1R AGONISTS IN DECREASING HEPATIC STEATOSIS AND APOPTOSIS IN OB/OB MICE UNDERGOING ISCHEMIA REPERFUSION INJURY
    Gupta, Nitika A.
    Kwun, Jean
    Kirk, Allan D.
    Anania, Frank A.
    Romero, Rene
    Knechtle, Stuart J.
    HEPATOLOGY, 2010, 52 (04) : 1041A - 1042A
  • [6] A Nonsynonymous Variant in GLP-1R Is Associated with Decreased Risk of Type 2 Diabetes in Koreans
    Kwak, Soo Heon
    Chae, Jeesoo
    Yoon, Jiwon
    Choi, Sunghee
    Lim, Soo
    Moon, Min Kyong
    Cho, Young Min
    Jang, Hak Chul
    Jang, Yoon Shin
    Kang, Hyun Min
    Kim, Jong-Il
    Park, Kyong Soo
    DIABETES, 2018, 67
  • [7] Reduced GLP-1R Expression in Gastric Glands of Patients With Type 2 Diabetes Mellitus
    Broide, E.
    Bloch, O.
    Ben-Yehudah, G.
    Cantrell, D.
    Shirin, H.
    Rapoport, M. J.
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2014, 99 (09): : E1691 - E1695
  • [8] FTZ attenuates liver steatosis and fibrosis in the minipigs with type 2 diabetes by regulating the AMPK signaling pathway
    Wang, Hong
    Huang, Minyi
    Bei, Weijian
    Yang, Yiqi
    Song, Lixia
    Zhang, Dongxing
    Zhan, Wenjing
    Zhang, Yuzhen
    Chen, Xu
    Wang, Weixuan
    Wang, Lexun
    Guo, Jiao
    BIOMEDICINE & PHARMACOTHERAPY, 2021, 138
  • [9] Loganin alleviates myocardial ischemia-reperfusion injury through GLP-1R/NLRP3-mediated pyroptosis pathway
    Li, Wenfan
    Fan, Pei
    Wang, Xiaobo
    Tang, Haifeng
    ENVIRONMENTAL TOXICOLOGY, 2023, 38 (11) : 2730 - 2740
  • [10] The GLP-1 receptor agonist liraglutide alleviates type 2 diabetes-related diastolic dysfunction in a pyruvate dehydrogenase dependent manner
    Chan, J. S. F.
    Greenwell, A. A.
    Saed, C. T.
    Stenlund, M. J.
    Mangra-Bala, I. A.
    Dakhili, S.
    Yang, K.
    Gopal, K.
    Eaton, F.
    Ussher, J. R.
    DIABETOLOGIA, 2023, 66 (SUPPL 1) : S329 - S329
12345