Multivariate exome analysis identifies CXCR5-CXCL13 signaling as a key driver in early breast cancer development and prognosis

被引：0
|
作者：
Dill, Courtney D. [1 ]
Griffen, Tiara [1 ]
Young, Corey [1 ]
Carey, Kaylin [1 ]
Lillard, James W. [1 ]
机构：
[1] Morehouse Sch Med, Atlanta, GA USA
来源：
CANCER RESEARCH | 2019年 / 79卷 / 13期
关键词：
D O I：
10.1158/1538-7445.AM2019-1975
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1975
引用
收藏
页数：2
相关论文
共 34 条
  • [21] CXCL13 inhibition induce the apoptosis of MDA-MB-231 breast cancer cells through blocking CXCR5/ERK signaling pathway
    Ma, J-J
    Jiang, L.
    Tong, D-Y
    Ren, Y-N
    Sheng, M-F
    Liu, H-C
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2018, 22 (24) : 8755 - 8762
  • [22] Improved Outcome of High-Risk Early HER2 Positive Breast Cancer With High CXCL13-CXCR5 Messenger RNA Expression
    Razis, Evangelia
    Kalogeras, Konstantine T.
    Kotoula, Vassiliki
    Eleftheraki, Anastasia G.
    Nikitas, Nikitas
    Kronenwett, Ralf
    Timotheadou, Eleni
    Christodoulou, Christos
    Pectasides, Dimitrios
    Gogas, Helen
    Wirtz, Ralph M.
    Makatsoris, Thomas
    Bafaloukos, Dimitrios
    Aravantinos, Gerasimos
    Televantou, Despina
    Pavlidis, Nicholas
    Fountzilas, George
    CLINICAL BREAST CANCER, 2012, 12 (03) : 183 - 193
  • [23] Transcriptome network analysis identifies co-expressed CXCL13, CXCR5, and associated genes contributes to the aggressive phenotype of TNBC
    Dill, Courtney Denise
    Dammer, Eric
    Griffen, Tiara L.
    Young, Corey D.
    Carey, Kaylin
    Nunez, Sha'Kayla
    Lillard, James
    JOURNAL OF IMMUNOLOGY, 2020, 204 (01):
  • [24] IRF5 is a novel regulator of CXCL13 expression in breast cancer that increases CXCR5+B and T cell trafficking to the tumor
    Pimenta, Erica
    De, Saurav
    Feng, Di
    Hall, Kelly
    Ran, Sophia
    Barnes, Betsy
    JOURNAL OF IMMUNOLOGY, 2014, 192
  • [25] CXCL13-CXCR5 co-expression regulates epithelial to mesenchymal transition of breast cancer cells during lymph node metastasis
    Biswas, Subir
    Sengupta, Suman
    Chowdhury, Sougata Roy
    Jana, Samir
    Mandal, Gunjan
    Mandal, Palash Kumar
    Saha, Nipun
    Malhotra, Vivek
    Gupta, Arnab
    Kuprash, Dmitry V.
    Bhattacharyya, Arindam
    BREAST CANCER RESEARCH AND TREATMENT, 2014, 143 (02) : 265 - 276
  • [26] RelA driven co-expression of CXCL13 and CXCR5 is governed by a multifaceted transcriptional program regulating breast cancer progression
    Biswas, Subir
    Chowdhury, Sougata Roy
    Mandal, Gunjan
    Purohit, Suman
    Gupta, Arnab
    Bhattacharyya, Arindam
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2019, 1865 (02): : 502 - 511
  • [27] CXCL13–CXCR5 co-expression regulates epithelial to mesenchymal transition of breast cancer cells during lymph node metastasis
    Subir Biswas
    Suman Sengupta
    Sougata Roy Chowdhury
    Samir Jana
    Gunjan Mandal
    Palash Kumar Mandal
    Nipun Saha
    Vivek Malhotra
    Arnab Gupta
    Dmitry V. Kuprash
    Arindam Bhattacharyya
    Breast Cancer Research and Treatment, 2014, 143 : 265 - 276
  • [28] Erratum to: CXCL13–CXCR5 co-expression regulates epithelial to mesenchymal transition of breast cancer cells during lymph node metastasis
    Subir Biswas
    Suman Sengupta
    Sougata Roy Chowdhury
    Samir Jana
    Gunjan Mandal
    Palash Kumar Mandal
    Nipun Saha
    Vivek Malhotra
    Arnab Gupta
    Dmitry V. Kuprash
    Arindam Bhattacharyya
    Breast Cancer Research and Treatment, 2016, 155 : 615 - 616
  • [29] Improved Outcome of High-Risk Early HER2 Positive Breast Cancer With High CXCL13-CXCR5 Messenger RNA Expression (vol 12, pg 183, 2012)
    Razis
    CLINICAL BREAST CANCER, 2012, 12 (05) : 386 - 386
  • [30] IRF5 is a novel regulator of CXCL13 expression in breast cancer that regulates CXCR5+ B- and T-cell trafficking to tumor-conditioned media
    Pimenta, Erica Maria
    De, Saurav
    Weiss, Ryan
    Feng, Di
    Hall, Kelly
    Kilic, Sarah
    Bhanot, Gyan
    Ganesan, Shridar
    Ran, Sophia
    Barnes, Betsy J.
    IMMUNOLOGY AND CELL BIOLOGY, 2015, 93 (05): : 486 - 499
1234