Detection of receptor-ligand interactions with an GHz impedance biosensor system

被引：0
|
作者：
Schlecht, U. [1 ]
Gronewold, T. M. A. [1 ]
Malave, A. [1 ]
Tewes, M. [1 ]
Loehndorf, M. [1 ]
机构：
[1] Ctr Adv European Studies & Res, D-53175 Bonn, Germany
来源：
2006 IEEE SENSORS, VOLS 1-3 | 2006年
关键词：
D O I：
暂无
中图分类号：
O42 [声学];
学科分类号：
070206 ; 082403 ;
摘要：
Nanogap impedance biosensors with electrode separation of 75 nm have been used for the specific detection of biological interactions. Different model systems, such as thrombin - anti-thrombin antibody, and Rev-peptide - antiRev aptamer are presented. In order to improve the signal-to-noise ratio the use of reference sensors has been explored. The interaction of prostate specific antigen (PSA) to an anti-PSA antibody is shown to demonstrate the detection at concentrations as low as 10 nM.
引用
收藏
页码：255 / +
页数：2
相关论文
共 50 条
  • [31] Two-dimensional measurements of receptor-ligand interactions
    Zheng, Songjie
    Zou, Min
    Shao, Yingfeng
    Wu, Huaping
    Wu, Helong
    Wang, Xiaohuan
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2023, 10
  • [32] Modelling of ORL1 receptor-ligand interactions
    Milan Senćanski
    Milovan D. Ivanović
    Ljiljana Došen-Mićović
    Chemical Papers, 2014, 68 : 1305 - 1316
  • [33] Receptor-ligand interactions underlying RBC invasion in Babesia
    Lobo, C. A.
    Cursino-Santos, J. R.
    Rodriguez, M.
    Ord, R.
    Singh, M.
    STATE OF THE ART PRESENTATIONS 33RD INTERNATIONAL CONGRESS OF THE INTERNATIONAL SOCIETY OF BLOOD TRANSFUSION, IN CONJUNCTION WITH THE 33RD CONGRESS OF THE KSBT AND 2014 CONGRESS OF THE KOREAN HEMATOLOGY SOCIETIES, VOL 10, NO S1, 2015, 10 (S1): : 173 - 180
  • [34] Kinetic-mechanics coupling of receptor-ligand interactions
    Zhu, C
    Chesla, SE
    Piper, JW
    PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 1996, 65 : PD205 - PD205
  • [35] Direct Binding Methods to Measure Receptor-Ligand Interactions
    Ray, Manisha
    Sayeed, Aryana
    Ganshert, Madeline
    Saha, Arjun
    JOURNAL OF PHYSICAL CHEMISTRY B, 2023, 128 (01): : 3 - 19
  • [36] Candida-host cell receptor-ligand interactions
    Filler, Scott G.
    CURRENT OPINION IN MICROBIOLOGY, 2006, 9 (04) : 333 - 339
  • [37] Targeting solute carriers to modulate receptor-ligand interactions
    Sijben, Hubert J.
    Superti-Furga, Giulio
    IJzerman, Adriaan P.
    Heitman, Laura H.
    TRENDS IN PHARMACOLOGICAL SCIENCES, 2022, 43 (05) : 358 - 361
  • [38] The flexibility-complementarity dichotomy in receptor-ligand interactions
    Sun, Hongmei
    Hunter, Christopher A.
    Llamas, Eva Marina
    CHEMICAL SCIENCE, 2015, 6 (02) : 1444 - 1453
  • [39] Construction of a model receptor-ligand system.
    Saltmarsh, J
    Sun, S
    Mallik, S
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1998, 215 : U24 - U24
  • [40] Computational strategies for modeling receptor flexibility in studies of receptor-ligand interactions
    Wade, RC
    Lüdemann, S
    STRUCTURE-BASED DRUG DESIGN: EXPERIMENTAL AND COMPUTATIONAL APPROACHES, 1998, 352 : 41 - 52
12345