Modulation of thermal pain-related brain activity with virtual reality: evidence from fMRI

被引：223

作者：

Hoffman, HG

Richards, TL

Coda, B

Bills, AR

Blough, D

Richards, AL

Sharar, SR

机构：

[1] Univ Washington, Human Interface Technol Lab, Seattle, WA 98195 USA

[2] Univ Washington, Dept Radiol, Seattle, WA 98195 USA

[3] Univ Washington, Dept Pharm, Seattle, WA 98195 USA

[4] Univ Washington, Dept Anesthesiol, Seattle, WA 98104 USA

来源：

NEUROREPORT | 2004年 / 15卷 / 08期

关键词：

analgesia; anterior cingulate cortex; fMRI; pain; somatosensory cortex; virtual reality;

D O I：

10.1097/01.wnr.0000127826.73576.91

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

This study investigated the neural correlates of virtual reality analgesia. Virtual reality significantly reduced subjective pain ratings (i.e. analgesia). Using fMRI, pain-related brain activity was measured for each participant during conditions of no virtual reality and during virtual reality (order randomized). As predicted, virtual reality significantly reduced pain-related brain activity in all five regions of interest; the anterior cingulate cortex, primary and secondary somatosensory cortex, insula, and thalamus (p<0.002, corrected). Results showed direct modulation of human brain pain responses by virtual reality distraction.

引用

页码：1245 / 1248

页数：4

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