Synthesis of functionalized acetophenones by [3+3] cyclizations of 1,3-bis-silyl enol ethers with 2-acetyl-3-silyloxyalk-2-en-1-ones

被引：21
|
作者：
Dede, R [1 ]
Langer, P [1 ]
机构：
[1] Univ Greifswald, Inst Chem & Biochem Ernst Moritz Arndt, D-17487 Greifswald, Germany
来源：
TETRAHEDRON LETTERS | 2004年 / 45卷 / 50期
关键词：
acetophenones; cyclizations; regioselectivity; silyl enol ethers;
D O I：
10.1016/j.tetlet.2004.10.104
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The TiCl4 mediated cyclization of 1,3-bis-silyl enol ethers with 2-acetyl-1-silyloxybut-1-en-3-one and 3-acetyl-4-silyloxypcnt-3-en-2-one, readily prepared from 3-formyl(acetylacetone) and triacetyl methane, afforded a variety of functionalized acetophenones. (C) 2004 Published by Elsevier Ltd.
引用
收藏
页码：9177 / 9179
页数：3
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