Establishment of CD137 humanized mouse model for efficacy assessment of agonistic anti-CD137 therapeutic antibodies

被引：0
|
作者：
Ouyang, Davy Xuesong
Chen, Gang
Wang, Zhensheng
Zheng, Lei
An, Annie Xiaoyu
Wery, Jean-Pierre
Liu, Jay
Dong, Xin
Li, Henry Q. X.
机构：
来源：
CANCER RESEARCH | 2017年 / 77卷
关键词：
D O I：
10.1158/1538-7445.AM2017-1658
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1658
引用
收藏
页数：2
相关论文
共 50 条
  • [21] Combination of anti-CD73 and agonistic anti-CD137 antibody therapy leads to tumor regression
    Chen, Siqi
    Zhang, Bin
    JOURNAL OF IMMUNOLOGY, 2015, 194
  • [22] Rationale for anti-CD137 cancer immunotherapy
    Makkouk, Amani
    Chester, Cariad
    Kohrt, Holbrook E.
    EUROPEAN JOURNAL OF CANCER, 2016, 54 : 112 - 119
  • [23] Radiotherapy Enhances Antitumor Effect of Anti-CD137 Therapy in a Mouse Glioma Model
    Newcomb, Elizabeth W.
    Lukyanov, Yevgeniy
    Kawashima, Noriko
    Alonso-Basanta, Michelle
    Wang, Shu-Chi
    Liu, Mengling
    Jure-Kunkel, Maria
    Zagzag, David
    Demaria, Sandra
    Formenti, Silvia C.
    RADIATION RESEARCH, 2010, 173 (04) : 426 - 432
  • [24] In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb
    Murillo, Oihana
    Dubrot, Juan
    Palazon, Asis
    Arina, Ainhoa
    Azpilikueta, Arantza
    Alfaro, Carlos
    Solano, Sarai
    Ochoa, Maria C.
    Berasain, Carmen
    Gabari, Izaskun
    Perez-Gracia, Jose L.
    Berraondo, Pedro
    Hervas-Stubbs, Sandra
    Melero, Ignacio
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2009, 39 (09) : 2424 - 2436
  • [25] Agonistic anti-CD137 antibody treatment leads to antitumor response in mice with liver cancer
    Gauttier, Vanessa
    Judor, Jean-Paul
    Le Guen, Valentin
    Cany, Jeannette
    Ferry, Nicolas
    Conchon, Sophie
    INTERNATIONAL JOURNAL OF CANCER, 2014, 135 (12) : 2857 - 2867
  • [26] Anti-CD137 mAb therapy of multiple myeloma
    Guillerey, Camille
    de Andrade, Lucas Ferrari
    Vuckovic, Slavica
    Ritchie, David
    Chesi, Marta
    Bergsagel, Leif
    Hill, Geoffrey R.
    Martinet, Ludovic
    Smyth, Mark J.
    CANCER IMMUNOLOGY RESEARCH, 2016, 4 (01)
  • [27] Development of a unique anti-CD137 therapeutic antibody: Efficacy and safety profiles in mono and combination therapy
    Liu, Guizhong
    Cheung, Peter
    Chen, Jun
    She, Xiaohong
    Du, Felix Fangyong
    Luo, Peter
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35
  • [28] EVALUATION OF EFFICACY AND TOXICITY OF CD137 IMMUNOTHERAPY WITH URELUMAB-MIGG1 CHIMERIC ANTIBODY IN CD137 HUGEMM™
    Zhang, Hongjuan
    He, Daniel
    Zhang, Mingkun
    Feng, Xinhe
    An, Annie
    Ju, Cunxiang
    Li, Henry
    Ouyang, Davy
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 8 : A388 - A388
  • [29] Assessment of tissue biomarkers following anti-CD137 treatment in the EMT-6 mouse tumor model.
    Tsuchihashi, Zenta
    Hu, Beihong
    Girit, Emel
    Lewin, Anne
    Shuster, David
    Dito, Gennaro
    Wu, Shujian
    Jure-Kunkel, Maria
    CANCER RESEARCH, 2006, 66 (08)
  • [30] Therapeutic vaccination with tumor cells that engage CD137
    Hellstrom, KE
    Hellstrom, I
    JOURNAL OF MOLECULAR MEDICINE-JMM, 2003, 81 (02): : 71 - 86
12345