Chronic Kidney Disease in Agricultural Communities

被引:5
|
作者
Wilke, Russell A. [1 ]
Qamar, Mohammad [2 ]
Lupu, Roxana A. [3 ]
Gu, Shaopeng [4 ]
Zhao, Jing [5 ]
机构
[1] Univ South Dakota, Sanford Sch Med, Dept Internal Med, Vermillion, SD 57069 USA
[2] Sanford Med Ctr, Dept Nephrol & Transplantat, Sioux Falls, SD USA
[3] Sanford Med Ctr, Dept Clin Informat, Sioux Falls, SD USA
[4] South Dakota State Univ, Dept Math & Stat, Brookings, SD 57007 USA
[5] Ohio State Univ, Dept Biomed Informat, Columbus, OH 43210 USA
来源
AMERICAN JOURNAL OF MEDICINE | 2019年 / 132卷 / 10期
基金
美国国家卫生研究院;
关键词
Heavy metal; Herbicide; Pesticide; Toxic nephropathy; EXPOSURE ASSESSMENT; GLYPHOSATE; ETIOLOGY; EPIDEMIC;
D O I
10.1016/j.amjmed.2019.03.036
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Patients residing in agricultural communities have a high risk of developing chronic kidney disease. In the Great Plains, geo-environmental risk factors (eg, variable climate, temperature, air quality, water quality, and drought) combine with agro-environmental risk factors (eg, exposure to fertilizers, soil conditioners, herbicides, fungicides, and pesticides) to increase risk for toxic nephropathy. However, research defining the specific influence of agricultural chemicals on the progression of kidney disease in rural communities has been somewhat limited. By linking retrospective clinical data within electronic medical records to environmental data from sources like US Environmental Protection Agency, analytical models are beginning to provide insight into the impact of agricultural practices on the rate of progression for kidney disease in rural communities. (C) 2019 Elsevier Inc. All rights reserved.
引用
收藏
页码:E727 / E732
页数:6
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