Discovery and characterization of potent and selective inhibitors to human epithelial 15-lipoxygenase-2

被引：0
|
作者：
Jameson, J. Brian, II [2 ]
Kantz, Auric [2 ]
Jadhav, Ajit [1 ]
Simeonov, Anton [1 ]
Maloney, David [1 ]
Holman, Ted [2 ]
机构：
[1] NIH, Natl Ctr Adv Translat Sci, Rockville, MD USA
[2] Univ Calif Santa Cruz, Dept Chem & Biochem, Santa Cruz, CA 95064 USA
来源：
FASEB JOURNAL | 2014年 / 28卷 / 01期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
582.5
引用
收藏
页数：1
相关论文
共 50 条
  • [21] Discovery of natural alkaloids as potent and selective inhibitors against human carboxylesterase 2
    Zhao, Yi-Shu
    Qian, Xing-Kai
    Guan, Xiao-Qing
    Song, Pei-Fang
    Song, Yun-Qing
    He, Rong-Jing
    Sun, Meng-Ru
    Wang, Xiu-Yang
    Zou, Li-Wei
    Ge, Guang-Bo
    BIOORGANIC CHEMISTRY, 2020, 105
  • [22] Tryptamine and homotryptamine-based sulfonamides as potent and selective inhibitors of 15-lipoxygenase
    Weinstein, DS
    Liu, W
    Gu, ZX
    Langevine, C
    Ngu, K
    Fadnis, L
    Combs, DW
    Sitkoff, D
    Ahmad, S
    Zhuang, SB
    Chen, X
    Wang, FL
    Loughney, DA
    Atwal, KS
    Zahler, R
    Macor, JE
    Madsen, CS
    Murugesan, N
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (05) : 1435 - 1440
  • [23] 15-lipoxygenase-2 expression in human macrophages induces chemokine secretion and T cell migration
    Danielsson, Kristina Noren
    Rydberg, Ellen Knutsen
    Ingelsten, Madeleine
    Akyurek, Levent M.
    Jirholt, Pernilla
    Ullstrom, Christina
    Forsberg, Gun-Britt
    Boren, Jan
    Wiklund, Olov
    Hulten, Lillemor Mattsson
    ATHEROSCLEROSIS, 2008, 199 (01) : 34 - 40
  • [24] Indolizines as novel potent inhibitors of 15-lipoxygenase
    Gundersen, LL
    Malterud, KE
    Negussie, AH
    Rise, F
    Teklu, S
    Ostby, OB
    BIOORGANIC & MEDICINAL CHEMISTRY, 2003, 11 (24) : 5409 - 5415
  • [25] Promoter activation of 15-Lipoxygenase-2 by radiation in prostate cancer cells
    Feng, Ying
    Yang, Qiuhui
    Wang, Dian
    CANCER RESEARCH, 2006, 66 (08)
  • [26] Discovery of tri(indolyl)methanes as potent and selective inhibitors against human carboxylesterase 2
    Li, Wei-Ran
    Mu, Jie
    Wang, An-Qi
    Su, Qi-Liang
    Li, Ming-Hang
    Lu, Cheng-Wei
    Zou, Li-Wei
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 307
  • [27] Discovery, development and characterization of potent and selective USP11 inhibitors
    Kayastha, Forum
    Kapadia, Bandish
    Herrington, Noah B.
    Roychowdhury, Anirban
    Kellogg, Glen E.
    Gartenhaus, Ronald B.
    CANCER RESEARCH, 2023, 83 (08)
  • [28] 15-lipoxygenase-2 is expressed in human atherosclerotic plaques and regulated by hypoxia in human macrophages:: Implications for LDL oxidation
    Rydberg, E
    Krettek, A
    Ullström, C
    Ekstrom, K
    Svensson, PA
    Carlsson, LM
    Jönsson-Rylander, AC
    Hansson, GI
    Wiklund, O
    Ohlsson, BG
    Hultén, LM
    CIRCULATION, 2004, 110 (17) : 282 - 282
  • [29] Tumor-suppressing 15-Lipoxygenase-2: Time for prime time?
    Guo, Yande
    Nie, Daotai
    CELL CYCLE, 2014, 13 (12) : 1836 - 1837
  • [30] Discovery of imidazopyridazinecarbonitriles as potent, selective inhibitors of CK2.
    Fink, Brian
    Gavai, Ashvinikumar
    Kim, Soong-Hoon
    Zhao, Yufen
    Purandare, Ashok
    Vite, Gregory
    Tokarski, John
    Yu, Chiang
    Henley, Benjamin
    Fargnoli, Joseph
    Desilva, Heshani
    Ross-MacDonald, Petra
    Rupnow, Brent
    Wong, Tai W.
    MOLECULAR CANCER THERAPEUTICS, 2013, 12 (11)
12345