Antifungal therapy of murine Aspergillus terreus infection

被引：37
|
作者：
Graybill, JR [1 ]
Hernandez, S [1 ]
Bocanegra, R [1 ]
Najvar, LK [1 ]
机构：
[1] Univ Texas, Hlth Sci Ctr, Dept Med, Div Infect Dis, San Antonio, TX 78229 USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2004年 / 48卷 / 10期
关键词：
D O I：
10.1128/AAC.48.10.3715-3719.2004
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Aspergillus terreus is a species which is being seen increasingly frequently and which is highly resistant to amphotericin B in vitro and clinically. We evaluated amphotericin B, caspofungin, and posaconazole in a murine model of acute invasive aspergillosis. Caspofungin and posaconazole both appeared beneficial and may be reasonable treatment alternatives for infection with A. terreus.
引用
收藏
页码：3715 / 3719
页数：5
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