Development and validation of an NGS-based assay to detect all classes of genomic alterations in circulating tumor cells (CTCs) from patients with solid tumors

被引：0
|
作者：
Welsh, Allison [1 ]
Frampton, Garrett M. [1 ]
Chalmers, Zachary R. [1 ]
Sperger, Jamie [2 ]
Yelensky, Roman [1 ]
Lipson, Doron [1 ]
Otto, Geoff [1 ]
Strotman, Lindsay [3 ]
Berry, Scott [3 ]
Pezzi, Hannah [3 ]
Traynor, Anne [2 ]
Beebe, David J. [3 ]
Miller, Vincent A. [1 ]
Lang, Joshua M. [2 ]
Stephens, Philip J. [1 ]
机构：
[1] Fdn Med Inc, Cambridge, MA USA
[2] Univ Wisconsin, Carbone Canc Ctr, Madison, WI USA
[3] Univ Wisconsin, Dept Biomed Engn, Madison, WI USA
来源：
CANCER RESEARCH | 2015年 / 75卷
关键词：
D O I：
10.1158/1538-7445.AM2015-1602
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1602
引用
收藏
页数：2
相关论文
共 39 条
  • [31] Development and validation of a real-time multiplex PCR assay for the simultaneous quantification of CK-19, MAGE-A3, HER-2 and PBGD in circulating tumor cells of breast cancer patients
    Strati, A.
    Markou, A.
    Malamos, N.
    Georgoulias, V.
    Lianidou, E. S.
    EJC SUPPLEMENTS, 2010, 8 (07): : 93 - 93
  • [32] Development and validation of a real-time multiplex PCR assay for the simultaneous quantification of CK-19, MAGE-A3, HER-2 and PBGD in circulating tumor cells of breast cancer patients
    Strati, Areti D.
    Markou, Athina N.
    Malamos, Nikos
    Georgoulias, Vasilis
    Lianidou, Evi
    CANCER RESEARCH, 2010, 70
  • [33] Comprehensive Genomic Analysis of Patients With Non-Small-Cell Lung Cancer Using Blood-Based Circulating Tumor DNA Assay: Findings From the BFAST Database of a Single Center in Taiwan
    Wang, Hsin-Yi
    Ho, Chao-Chi
    Lin, Yen-Ting
    Liao, Wei-Yu
    Chen, Chung-Yu
    Shih, Jin-Yuan
    Yu, Chong-Jen
    JCO PRECISION ONCOLOGY, 2024, 8
  • [34] Development and Analytical Validation of a 6-Plex Reverse Transcription Droplet Digital PCR Assay for the Absolute Quantification of Prostate Cancer Biomarkers in Circulating Tumor Cells of Patients with Metastatic Castration-Resistant Prostate Cancer
    Zavridou, Martha
    Smilkou, Stavroula
    Tserpeli, Victoria
    Sfika, Aggeliki
    Bournakis, Evangelos
    Strati, Areti
    Lianidou, Evi
    CLINICAL CHEMISTRY, 2022, 68 (10) : 1323 - 1335
  • [35] Development and analytical validation of a novel real-time multiplex RT-qPCR assay for the simultaneous quantification of ER, PR, HER-2 and EGFR mRNA expression in circulating tumor cells of breast cancer patients
    Strati, Areti D.
    Lianidou, Evi S.
    CANCER RESEARCH, 2014, 74 (19)
  • [36] Erlotinib plus bevacizumab in patients with metastatic solid tumors with EGFR amplification: Results from the KOSMOS-II (KOrean Precision Medicine Networking Group Study of MOlecular profiling guided therapy based on genomic alterations in advanced solid tumors, KCSG AL 22-09)
    Lee, J. W.
    Lee, Y-g.
    Lee, G-w.
    Jung, H. A.
    Kim, K-p.
    Kim, T-y.
    Ryu, H.
    Ryu, M. H.
    Ahn, M. S.
    Yun, H.
    Ahn, S.
    Shim, H. S.
    Kim, J.
    Sim, J.
    Kim, S. Y.
    Kim, J. H.
    Lee, S.
    ANNALS OF ONCOLOGY, 2024, 35 : S1580 - S1580
  • [37] Utilizing phenotypic characteristics of metastatic brain tumors to improve the probability of detecting circulating tumor DNA from cerebrospinal fluid in non-small-cell lung cancer patients: development and validation of a prediction model in a prospective cohort study
    Li, M.
    Hou, X.
    Zheng, L.
    Ma, Y.
    Li, D.
    Lv, Y.
    Chen, J.
    Zheng, W.
    Shao, Y.
    Mou, Y.
    Chen, L.
    ESMO OPEN, 2022, 7 (01)
  • [38] Development and Analytical Validation of a 6-Plex Reverse Transcription Droplet Digital PCR Assay for the Absolute Quantification of Prostate Cancer Biomarkers in Circulating Tumor Cells of Patients with Metastatic Castration-Resistant Prostate Cancer (vol 68, pg 1323, 2022)
    Zavridou, Martha
    Smilkou, Stavroula
    Tserpeli, Victoria
    Sfika, Aggeliki
    Bournakis, Evangelos
    Strati, Areti
    Lianidou, Evi
    CLINICAL CHEMISTRY, 2023, 69 (06) : 669 - 669
  • [39] Development, analytical and clinical validation of a novel multiplex RT-qPCR assay for the simultaneous quantification of four AR splice variants (AR-FL, AR-V7, AR-567es and ARtotal) in circulating tumor cells of mCRPC patients
    Strati, A.
    Zavridou, M.
    Angelidis, I
    Bournakis, E.
    Georgoulias, V
    Lianidou, E.
    CLINICAL & EXPERIMENTAL METASTASIS, 2018, 35 (03) : 205 - 205
1234