Transition metal catalysed alkylation of pyridines and indoles

被引：62
|
作者：
Grigg, R
Savic, V
机构：
[1] Molec. Innov., Diversity Automat. S., School of Chemistry
来源：
TETRAHEDRON LETTERS | 1997年 / 38卷 / 32期
基金：
英国工程与自然科学研究理事会;
关键词：
D O I：
10.1016/S0040-4039(97)01260-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Heating 3- or 4-acetyl pyridine with alkenes in toluene in the presence of 5-10 mol% of RuH2CO(PPh3)(3) afforded the mono- or a mixture of mono- and di-alkylated products in good yield. Alkylation of acetylindole derivatives was also achieved with similar efficiency. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码：5737 / 5740
页数：4
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