Frequency doubling technology perimetry in open-angle glaucoma eyes with hemifield visual field damage: Comparison of high-tension and normal-tension groups

Purpose: To evaluate the performance of frequency doubling technology (FDT) perimetry in open-angle glaucoma eyes with hemifield visual field damage and to compare it between openangle glaucoma with high pressure [high-tension glaucoma (HTG)] and those with normal pressure [normal-tension glaucoma (NTG)] groups. Methods: FDT perimetry with the N-30 full threshold protocol and standard automated perimetry (SAP) using the Humphrey Field Analyzer with the 30-2 full threshold protocol were performed in 20 eyes of 20 HTG patients and 36 eyes of 36 NTG patients with visual field damage confirmed with SAP in only one hemifield. Results: There was no significant difference in demographics, the Heidelberg Retina Tomography indices, and the Humphrey Field Analyzer indices between HTG and NTG groups. Regarding the FDT perimetry results, mean deviation in the global field (P = 0.009) and mean sensitivity in the SAP-spared (P = 0.001) and SAP-impaired (P = 0.011) hemifields were lower: the numbers of FDT abnormal test points (probability of abnormality < 5%) in the SAP-spared hemifield were significantly greater (P = 0.005) in HTG than in NTG groups. Eyes in which FDT results of the SAP-spared hemifield were judged as abnormal was more frequent in HTG groups (P = 0.007). Conclusions: The performance of FDT perimetry to detect early or preperimetric glaucomatous functional changes should be different between HTG and NTG eyes.