Phosphorelay as the sole physiological route of signal transmission by the arc two-component system of Escherichia coli

被引：81
|
作者：
Kwon, O [1 ]
Georgellis, D [1 ]
Lin, ECC [1 ]
机构：
[1] Harvard Univ, Sch Med, Dept Microbiol & Mol Genet, Boston, MA 02115 USA
来源：
JOURNAL OF BACTERIOLOGY | 2000年 / 182卷 / 13期
关键词：
D O I：
10.1128/JB.182.13.3858-3862.2000
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The Are two-component system, comprising a tripartite sensor kinase (ArcB) and a response regulator (ArcA), modulates the expression of numerous genes involved in respiratory functions. In this study, the steps of phosphoryl group transfer from phosphorylated ArcB to ArcA were examined in vivo by using single copies of wild-type and mutant arcB alleles, The results indicate that the signal transmission occurs solely by His-Asp His-Asp phosphorelay.
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页码：3858 / 3862
页数：5
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