Successful treatment of donor-derived hepatitis C infection in a lung transplant recipient

被引：13

作者：

Theodoropoulos, Nicole ^{[1
]}

Whitson, Bryan A. ^{[2
]}

Martin, Stanley I. ^{[3
]}

Pouch, Stephanie ^{[4
]}

Pope-Harman, Amy ^{[5
]}

机构：

[1] UMass Mem Med Ctr, Dept Med, Div Infect Dis & Immunol, Worcester, MA USA

[2] Ohio State Univ, Dept Surg, Div Cardiac Surg, Columbus, OH 43210 USA

[3] Geisinger Hlth Syst, Divs Infect Dis, Danville, PA USA

[4] OSU, Div Infect Dis, Dept Internal Med, Columbus, OH USA

[5] OSU, Div Pulm Allergy Crit Care & Sleep Med, Dept Internal Med, Columbus, OH USA

来源：

TRANSPLANT INFECTIOUS DISEASE | 2017年 / 19卷 / 02期

关键词：

direct-acting antivirals; donor-derived infection; hepatitis C; lung transplant; HUMAN-IMMUNODEFICIENCY-VIRUS; GENOTYPE; ORGAN; TRANSMISSION; SOFOSBUVIR; SIMEPREVIR; RIBAVIRIN;

D O I：

10.1111/tid.12659

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Data are limited regarding the use of direct-acting antivirals for treatment of hepatitis C infection post lung transplant, especially in a donor-derived infection. We present a case of a lung transplant recipient with donor-derived hepatitis C that was successfully treated with a 12-week regimen of simeprevir and sofosbuvir. This case reiterates the importance of screening recipients of increased-risk donor organs for disease transmission and the value of early therapy.

引用

页数：3

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