ANTIMICROBIAL ACTIVITY SCREENING OF BENZOTHIAZOLYL-PHENOTHIAZINE DERIVATIVES

被引：0

作者：

Grozav, Adriana ^{[1
]}

Zaharia, Valentin ^{[1
]}

Cristea, Castelia ^{[2
]}

Fit, Nicodim Iosif ^{[3
]}

机构：

[1] Iuliu Hatieganu Univ Med & Pharm, Fac Pharm, Victor Babes 41, RO-400012 Cluj Napoca, Romania

[2] Univ Babes Bolyai, Fac Chem & Chem Engn, RO-400028 Cluj Napoca, Romania

[3] Agr Sci & Vet Med Cluj Napoca, Fac Vet Med, Dept Microbiol, RO-400337 Cluj Napoca, Romania

来源：

STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA | 2015年 / 60卷 / 03期

关键词：

phenothiazine; benzothiazole; antibacterial; diffusion; broth dilution; minimal inhibitory concentration; MICROWAVE-ASSISTED SYNTHESIS; HYDRAZINOTHIAZOLES;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The antimicrobial activity of a series of benzothiazolyl-10H-phenothiazine derivatives against Gram positive Bacteria (Staphylococcus aureus and Bacillus cereus), Gram negative Bacteria (Escherichia coli, Salmonella enteritidis, Pseudomonas aeruginosa) and fungus Candida albicans respectively, was screened using diffusion method and minimal inhibitory concentrations (MIC) were assessed by broth serial dilution procedure. Candida albicans, Bacillus cereus and Pseudomonas aeruginosa were proved to be susceptible to the benzothiazolyl-10H-phenothiazine derivatives (MIC 0.02-1.3 mu g/mL)

引用

页码：283 / 288

页数：6

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