Novel catalytic kinetic resolution of racemic epoxides to allylic alcohols

被引：38
|
作者：
Gayet, A [1 ]
Bertilsson, S [1 ]
Andersson, PG [1 ]
机构：
[1] Uppsala Univ, Inst Chem, Dept Organ Chem, S-75121 Uppsala, Sweden
来源：
ORGANIC LETTERS | 2002年 / 4卷 / 22期
关键词：
D O I：
10.1021/ol025983e
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
graphic The kinetic resolution of racemic epoxides via catalytic enantioselective rearrangement to allylic alcohols was investigated. Using the U-salt of (1S,3R,4R)-3-(pyrrolidinyl)methyl-2-azabicyclo [2.2.1] heptane 1 as catalyst allowed both epoxides and allylic alcohols to be obtained in an enantioenriched form.
引用
收藏
页码：3777 / 3779
页数：3
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