Synthesis and characterization of steroidal 5′formyl [6,7-c] pyrazoles using Vilsmeier-Haack reagent

被引：0

作者：

Shamsuzzaman ^{[1
]}

Khan, M. Shaheen ^{[1
]}

Tabassum, Zishan ^{[1
]}

Alam, Mahboob ^{[1
]}

机构：

[1] Aligarh Muslim Univ, Dept Chem, Aligarh 202002, Uttar Pradesh, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2009年 / 48卷 / 08期

关键词：

Steroidal tosylhydrazone; heterocycles; Vilsmeier-Haack reagent; pyrazoles; DERIVATIVES;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The preparation of hitherto unknown steroidal heterocycles containing pyrazole moiety fused to 6,7-position of the steroidal nucleus is described. These heterocycles have been prepared by the action of Vilsmeier reagent with steroidal tosylhydrazone in DMF. The structures of the compounds have been established on the basis of their elemental analysis and spectral data. A general mechanistic scheme for these reactions is also suggested based on current and previous results.

引用

页码：1183 / 1186

页数：4

共 50 条

[41] Synthesis of 6-amino-4-(4-methoxyphenyl)-5-cyano-3-methyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles using disulfonic acid imidazolium chloroaluminate as a dual and heterogeneous catalyst
Moosavi-Zare, Ahmad Reza
Zolfigol, Mohammad Ali
Noroozizadeh, Ehsan
Tavasoli, Mahsa
Khakyzadeh, Vahid
Zare, Abdolkarim
NEW JOURNAL OF CHEMISTRY, 2013, 37 (12) : 4089 - 4094
[42] Tricyclic pyrazoles.: 3.: Synthesis, biological evaluation, and molecular modeling of analogues of the cannabinoid antagonist 8-chloro-1-(2′,4′-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide
Murineddu, G
Ruiu, S
Loriga, G
Manca, I
Lazzari, P
Reali, R
Pani, L
Toma, L
Pinna, GA
JOURNAL OF MEDICINAL CHEMISTRY, 2005, 48 (23) : 7351 - 7362
[43] SYNTHESIS OF [RE(ETA-C6H6)(ETA-5-C8H11)], [RE(ETA-C6H6)(ETA-5-C8H11)H]BF4, AND [RE(ETA-C6H6)(ETA-4-C8H12)PH] USING RHENIUM ATOMS - CHARACTERIZATION BY APPLICATION OF A MODIFIED HETERONUCLEAR C-13-H-1 J-RESOLVED TWO-DIMENSIONAL NUCLEAR-MAGNETIC-RESONANCE EXPERIMENT
DEROME, AE
GREEN, MLH
OHARE, D
JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1986, (02): : 343 - 346
[44] Visible-light photocatalytic removal of betamethasone using heterogeneous CdSe/Bi2MoO6/g-C3N5 nanophotocatalyst: Synthesis, characterization, Thermodynamic and kinetics analysis
Beirami, Peyman
Derakhshanfard, Fahimeh
Gharbani, Parvin
Amirkhani, Leila
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2023, 444
[45] MECHANISM OF STEROIDAL ENOL ETHER FORMATION - CONFIGURATION OF TRITIUM AT C-6 OF ESTRA-1,3,5(6)-TRIEN-3-OL-17-ONE-6,7-H-3 AS ESTABLISHED DURING SYNTHESIS OF 19-NOR-17ALPHA-PREGNA-3,5-DIEN-20-YN-17-OL-7-H-3 17-ACETATE
MERRILL, EJ
VERNICE, GG
JOURNAL OF LABELLED COMPOUNDS, 1973, 9 (01): : 43 - 52
[46] SYNTHESIS AND CHARACTERIZATION OF 3-(4-ARYL-5H-6,7,-DIHYDROCYCLOPENTA[B]PYRIDIN-2-YL), 3-(4-ARYL-5,6,7,8-TETRAHYDROQUINOLIN-2-YL) AND 3-(5-HYDROXY-BIPHENYL-3-YL) COUMARINS USING PIPERIDINE AS A CATALYST
Pandya, Mahesh K.
Chhasatia, Mehulsinh R.
Vala, Nileshkumar D.
Parekh, Tapan H.
HETEROCYCLIC LETTERS, 2020, 10 (02): : 333 - 340
[47] Spectrophotometric Determination of Trace Concentrations of Copper in Waters Using the Chromogenic Reagent 4-Amino-3-Mercapto-6-[2-(2-Thienyl)Vinyl]-1,2,4-Triazin-5(4H)-One: Synthesis, Characterization, and Analytical Applications
Alharthi, Salman S.
Al-Saidi, Hamed M.
APPLIED SCIENCES-BASEL, 2020, 10 (11):
[48] AXIALLY ASYMMETRIC METAL ALKYLS .2. SYNTHESIS OF THE DI-GRIGNARD REAGENT [(MG(THF)NCL)2R] [THF = TETRAHYDROFURAN, R = (2-CH2C6H4)22-] AND 6,7-DIHYDRO-5H-DIBENZO[C,E]-SILEPINES AND -STANNEPINES-[SNPH2([2-CH(SIME3)C6H4]2)] X-RAY CRYSTAL-STRUCTURES OF [SNPH2R] AND DELTA-SS-[SNPH2([2-CH(SIME3)C6H4]2)] AND LAMBDA-RR-[SNPH2([2-CH(SIME3)C6H4]2)]EP
ENGELHARDT, LM
LEUNG, WP
TWISS, P
WHITE, AH
RASTON, CL
JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1984, (03): : 331 - 340
[49] SYNTHESIS AND CHARACTERIZATION OF AN EXCEPTIONALLY AIR-STABLE ORGANO-METALLIC NICKEL(II) COMPLEX OF THE ORGANO-LITHIUM REAGENT (C6H5)2P(S)CH2LI - THE X-RAY CRYSTAL-STRUCTURE OF CHLORO(TRIPHENYLPHOSPHINE)[DIPHENYL(METHYLENE)-PHOSPHORANYLTHIO-S,C]NICKEL(II), NICH2P(S)PH2(PPH3)CL
MAZANY, AM
FACKLER, JP
ORGANOMETALLICS, 1982, 1 (05) : 752 - 753
[50] Synthesis and characterization of tributyltin(IV) complexes of 2-[(E)-2-(3-formyl-4-hydroxyphenyl)-1-diazenyl]benzoic acid and 4-[((E)-1-{2-hydroxy-5-[(E)-2-(2-carboxyphenyl)-1-diazenyl]phenyl}methylidene)amino]aryls -: crystal structures of polymeric (Bu3Sn[O2CC6H4{N=N(C6H3-4-OH-5-CHO)}-o])n and (Bu3Sn[O2CC6H4{N=N(C6H3-4-OH-C(H)=NC6H4Cl-4))}-o])n -: toxicity studies on the second instar of Aedes aegypti mosquito larvae
Baul, TSB
Singh, KS
Song, XQ
Zapata, A
Eng, G
Lycka, A
Linden, A
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2004, 689 (25) : 4702 - 4711

← 1 2 3 4 5 →