Colorimetric Sensing of α-Amino Acids and Its Application for the "Label-Free" Detection of Protease

被引：63
|
作者：
Lou, Xiaoding [2 ]
Zhang, Liyao [1 ]
Qin, Jingui [2 ]
Li, Zhen [2 ]
机构：
[1] Wuhan Univ, Coll Life Sci, Wuhan 430072, Peoples R China
[2] Wuhan Univ, Dept Chem, Hubei Key Lab Organ & Polymer Optoelect Mat, Wuhan 430072, Peoples R China
来源：
LANGMUIR | 2010年 / 26卷 / 03期
基金：
美国国家科学基金会;
关键词：
CONJUGATED POLYMERS; CHIRAL RECOGNITION; HIGH SELECTIVITY; FLUORESCENCE; SENSORS; WATER; HISTIDINE; PROBE; COORDINATION; CHEMOSENSOR;
D O I：
10.1021/la904138f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new indirect approach to explore sensitive colorimetric sensors toward alpha-amino acids is proposed: the pink solution of 1 and copper ions changed to colorless immediately upon the addition of alpha-amino acids. As the hydrolysis of bovine serum albumin (BSA) with the aid of trypsin produces alpha-amino acids, the complex of 1/Cu2+/BSA could act as a label-free, sensitive, selective sensor toward trypsin. The detection process could be visually observed by naked eyes.
引用
收藏
页码：1566 / 1569
页数：4
相关论文
共 50 条
  • [1] Label-Free Electrochemical Sensing Platform for the Detection of Protease
    Deng, Dehua
    Shi, Yunfeng
    Feng, Hongmei
    Chen, Qianqian
    Li, Dongxiao
    Liu, Lin
    INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, 2013, 8 (05): : 6933 - 6940
  • [2] Electrochemical strategies for the label-free detection of amino acids, peptides and proteins
    Herzog, Gregoire
    Arrigan, Damien W. M.
    ANALYST, 2007, 132 (07) : 615 - 632
  • [3] Kanamycin Adsorption on Gold Nanoparticles Dominates Its Label-Free Colorimetric Sensing with Its Aptamer
    Zhou, Jiaojiao
    Li, Yuqing
    Wang, Wenjing
    Lu, Zhicheng
    Han, Heyou
    Liu, Juewen
    LANGMUIR, 2020, 36 (39) : 11490 - 11498
  • [4] Label-free Colorimetric Sensing of α-Amino Acids Based on Surface-enhanced Photochromic Phenomena of Molybdenum (VI) Oxide Nanoparticles
    Yamamoto, Asami
    Adachi, Kenta
    BUNSEKI KAGAKU, 2017, 66 (09) : 639 - 646
  • [5] A Label-Free Colorimetric Aptasensor for Flavokavain B Detection
    Ke, Sisi
    Wang, Ningrui
    Chen, Xingyu
    Tian, Jiangwei
    Li, Jiwei
    Yu, Boyang
    SENSORS, 2025, 25 (02)
  • [6] Colorimetric sensing of cysteine using label-free silver nanoparticles
    Han, Cuiping
    Xu, Kai
    Liu, Qi
    Liu, Xiaohua
    Li, Jingjing
    SENSORS AND ACTUATORS B-CHEMICAL, 2014, 202 : 574 - 582
  • [7] Label-free silver nanoparticles for visual colorimetric detection of etimicin
    Li, Nan
    Gu, Yu
    Gao, Mengmeng
    Wang, Zilu
    Xiao, Deli
    Li, Yun
    Wang, Jing
    He, Hua
    ANALYTICAL METHODS, 2014, 6 (19) : 7906 - 7911
  • [8] Enhanced catalytic DNAzyme for label-free colorimetric detection of DNA
    Li, Tao
    Dong, Shaojun
    Wang, Erkang
    CHEMICAL COMMUNICATIONS, 2007, (41) : 4209 - 4211
  • [9] Label-free and pH-sensitive colorimetric materials for the sensing of urea
    Li, Lu
    Long, Yue
    Gao, Jin-Ming
    Song, Kai
    Yang, Guoqiang
    NANOSCALE, 2016, 8 (08) : 4458 - 4462
  • [10] A Novel Fluorescent Chemosensor for α-Amino Acids and Its Application for the Detection of Protease
    Cheng X.
    Qu S.
    Zhong Z.
    Cailiao Daobao/Materials Review, 2018, 32 (07): : 2486 - 2490
12345