Controlled release of drug molecules in metal-organic framework material HKUST-1

被引：60

作者：

Chen, Qing ^{[1
,3
]}

Chen, Qi-Wei ^{[1
,3
]}

Zhuang, Chong ^{[1
,3
]}

Tang, Piao-Ping ^{[2
]}

Lin, Ning ^{[1
,3
]}

Wei, Lian-Qiang ^{[2
]}

机构：

[1] Guangxi Univ Chinese Med, Coll Pharm, Nanning 530001, Peoples R China

[2] Hechi Univ, Coll Chem & Bioengn, Yizhou 546300, Peoples R China

[3] Guangxi Zhuang Yao Med Ctr Engn & Technol, Nanning 530200, Peoples R China

来源：

INORGANIC CHEMISTRY COMMUNICATIONS | 2017年 / 79卷

基金：

中国国家自然科学基金;

关键词：

Metal organic frameworks; HKUST-1; Drug delivery; Controlled release; ADSORPTION; COMPLEXES; LIGAND; MOF;

D O I：

10.1016/j.inoche.2017.03.027

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The Cu-3(BTC)(2) metal-organic framework (MOF) (BTC 1,3,5-benzenetricarboxylate), also known as HKUST-1, is one of the earliest reported stable MOFs with a very high surface area. In this study, HKUST-1 was used for the first time to absorb the pharmaceutical products of ibuprofen, anethole and guaiacol with loading amount of 034 g.g(-1), 038 g.g(-1) and 0.40 g.g(-1), respectively, which also showing good controlled drug release property. The result from this work provides a new attempt for HKUST-1 to be used as potential platform for drug delivery and release. (C) 2017 Published by Elsevier B.V.

引用

页码：78 / 81

页数：4

共 50 条

[1] Porosity Changes in a Metal-Organic Framework HKUST-1 by Controlled Hydrolysis
Choi, Sang Beom
Sim, Jaeung
Park, Hye Jeong
Kang, Eunyoung
Jung, Soon Gil
Kim, Jaheon
[J]. BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2016, 37 (05): : 767 - 770
[2] Rapid synthesis of metal-organic framework HKUST-1
You, Jia-Yong
Zhang, Tian-Yong
Liu, Yan-Feng
Li, Bin
Zhao, Zhen-Dong
Huang, Jun-Hao
[J]. Gao Xiao Hua Xue Gong Cheng Xue Bao/Journal of Chemical Engineering of Chinese Universities, 2015, 29 (05): : 1126 - 1132
[3] Stability of the adsorption properties of the metal-organic framework HKUST-1
Pribylov, A. A.
Murdmaa, K. O.
[J]. RUSSIAN CHEMICAL BULLETIN, 2022, 71 (02) : 240 - 243
[4] Thermomechanical properties of metal-organic framework HKUST-1 crystals
Wang, Bing
Ke, Jin
Zhang, Jin
[J]. JOURNAL OF MATERIALS CHEMISTRY A, 2024, 12 (25) : 15071 - 15081
[5] Modifying the Hydrophobic Properties of Metal-Organic Framework HKUST-1
Isaeva, V. I.
Chernyshev, V. V.
Sokolova, N. A.
Kapustin, G. I.
[J]. RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY A, 2018, 92 (12) : 2391 - 2395
[6] Stability of the adsorption properties of the metal-organic framework HKUST-1
A. A. Pribylov
K. O. Murdmaa
[J]. Russian Chemical Bulletin, 2022, 71 : 240 - 243
[7] Surface Termination of the Metal-Organic Framework HKUST-1: A Theoretical Investigation
Amirjalayer, Saeed
Tafipolsky, Maxim
Schmid, Rochus
[J]. JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2014, 5 (18): : 3206 - 3210
[8] Effective adsorption of chlorpyrifos pesticides by HKUST-1 metal-organic framework
Bharti Kangra
Anushree Jatrana
Sheetal Maan
Sonu Chauhan
Vinay Kumar
[J]. Journal of Chemical Sciences, 134
[9] Chemical principles underpinning the performance of the metal-organic framework HKUST-1
Hendon, Christopher H.
Walsh, Aron
[J]. CHEMICAL SCIENCE, 2015, 6 (07) : 3674 - 3683
[10] Controlled SBU Approaches to Isoreticular Metal-Organic Framework Ruthenium-Analogues of HKUST-1
Zhang, Wenhua
Kozachuk, Olesia
Medishetty, Raghavender
Schneemann, Andreas
Wagner, Ralph
Khaletskaya, Kira
Epp, Konstantin
Fischer, Roland A.
[J]. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2015, (23) : 3913 - 3920

← 1 2 3 4 5 →