IMMUNE CHECKPOINT BLOCKADE IMPACTS THE SUPPRESSIVE PHENOTYPE AND FUNCTION OF REGULATORY T CELLS IN AN ENDOGENOUS MOUSE LYMPHOMA MODEL

被引：0
|
作者：
Bauer, Vera [1 ]
Ahmetlic, Fatima [1 ]
Roecken, Martin [2 ]
Mocikat, Ralph [1 ]
Mocikat, Ralph [1 ]
机构：
[1] Helmholtz Zentrum Muenchen, Munich, Germany
[2] Eberhard Karls Univ Tuebingen, Tubingen, Germany
来源：
JOURNAL FOR IMMUNOTHERAPY OF CANCER | 2020年 / 8卷
关键词：
D O I：
10.1136/jitc-2020-SITC2020.0779
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
779
引用
收藏
页码：A467 / A468
页数：2
相关论文
共 50 条
  • [41] CD4 T cells and toxicity from immune checkpoint blockade
    Earland, Noah
    Zhang, Wubing
    Usmani, Abul
    Nene, Aishwarya
    Bacchiocchi, Antonella
    Chen, David Y.
    Sznol, Mario
    Halaban, Ruth
    Chaudhuri, Aadel A.
    Newman, Aaron M.
    IMMUNOLOGICAL REVIEWS, 2023, 318 (01) : 96 - 109
  • [42] Tumor-infiltrating γδ T cells as targets of immune checkpoint blockade in melanoma
    Di Simone, Marta
    Corsale, Anna Maria
    Toia, Francesca
    Shekarkar Azgomi, Mojtaba
    Di Stefano, Anna Barbara
    Lo Presti, Elena
    Cordova, Adriana
    Montesano, Luigi
    Dieli, Francesco
    Meraviglia, Serena
    JOURNAL OF LEUKOCYTE BIOLOGY, 2024, 115 (04) : 760 - 770
  • [43] Stromal Factors Modulate Immune Checkpoint Blockade on T Cells in Pancreatic Cancer
    Sharma, P.
    Garg, B.
    Ferrantella, A.
    Vaish, U.
    Sethi, V.
    Kurtom, S.
    Jacob, H.
    Ramakrishnan, S.
    Dawra, R.
    Saluja, A. K.
    Dudeja, V.
    PANCREAS, 2019, 48 (10) : 1520 - 1521
  • [44] A Transendocytosis Model of CTLA-4 Function Predicts Its Suppressive Behavior on Regulatory T Cells
    Hou, Tie Zheng
    Qureshi, Omar S.
    Wang, Chun Jing
    Baker, Jennifer
    Young, Stephen P.
    Walker, Lucy S. K.
    Sansom, David M.
    JOURNAL OF IMMUNOLOGY, 2015, 194 (05): : 2148 - 2159
  • [45] Regulatory T cells contribute to the immunosuppressive phenotype of neutrophils in a mouse model of chronic lymphocytic leukemia
    Agnieszka Goral
    Marta Sledz
    Aneta Manda-Handzlik
    Adrianna Cieloch
    Alicja Wojciechowska
    Mieszko Lachota
    Agnieszka Mroczek
    Urszula Demkow
    Radoslaw Zagozdzon
    Katarzyna Matusik
    Malgorzata Wachowska
    Angelika Muchowicz
    Experimental Hematology & Oncology, 12
  • [46] Regulatory T cells contribute to the immunosuppressive phenotype of neutrophils in a mouse model of chronic lymphocytic leukemia
    Goral, Agnieszka
    Sledz, Marta
    Manda-Handzlik, Aneta
    Cieloch, Adrianna
    Wojciechowska, Alicja
    Lachota, Mieszko
    Mroczek, Agnieszka
    Demkow, Urszula
    Zagozdzon, Radoslaw
    Matusik, Katarzyna
    Wachowska, Malgorzata
    Muchowicz, Angelika
    EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 12 (01)
  • [47] Phenotype and function of graft-vs-tumor conferring cells in a mouse lymphoma model.
    Ito, M
    Shizuru, JA
    BLOOD, 1998, 92 (10) : 436A - 437A
  • [48] Phenotype and function of T regulatory cells and their role in HIV infection
    Joshua, Fink
    Jeron, Andreas
    Brighenti, Susanna
    Michaelsson, Jakob
    Andersson, Jan
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2008, 68 (02) : 254 - 254
  • [49] Ablation of Interferon Regulatory Factor 4 in T Cells Induces "Memory" of Transplant Tolerance That is Irreversible by Immune Checkpoint Blockade.
    Zhang, H.
    Wu, J.
    Zou, D.
    Chen, W.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2019, 19 : 1044 - 1044
  • [50] Regulatory T cells, polymorphisms, and response to checkpoint blockade: From mechanisms to potential biomarkers
    Quezada, Sergio
    CLINICAL CANCER RESEARCH, 2018, 24 (17)
12345