Efficacy of IL-12 gene therapy for human lung cancer demonstrated in SCID mice co-engrafted with human PBL and human tumor cells

被引:0
|
作者
Hess, SD [1 ]
Egilmez, NK [1 ]
Bankert, RB [1 ]
机构
[1] New York State Dept Hlth, Roswell Pk Canc Inst, Buffalo, NY 14263 USA
来源
FASEB JOURNAL | 2000年 / 14卷 / 06期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:A1136 / A1136
页数:1
相关论文
共 50 条
  • [31] Establishment of a SCID mouse model for synergistic anti-tumor effect of human IL-12 and B7-1
    Gao, J
    Zhao, P
    Chen, XH
    Li, M
    Long, JQ
    Gu, AM
    Wu, XL
    Cao, GW
    Qi, ZT
    ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2003, 35 (06) : 529 - 535
  • [32] Suicide gene therapy of human breast cancer in SCID mice model by the regulation of Tet-On
    胡维新
    曾赵军
    罗赛群
    陈迁
    中华医学杂志(英文版), 2004, (03) : 115 - 120
  • [33] NOD-scid IL2R γnull mice engrafted with human peripheral blood mononuclear cells as a model to test therapeutics targeting human signaling pathways
    Zadeh-Khorasani, Maryam
    Nolte, Thomas
    Mueller, Thomas D.
    Pechlivanis, Markos
    Rueff, Franziska
    Wollenberg, Andreas
    Fricker, Gert
    Wolf, Eckhard
    Siebeck, Matthias
    Gropp, Roswitha
    JOURNAL OF TRANSLATIONAL MEDICINE, 2013, 11
  • [34] Human LT-α-mediated resistance to autoimmune diabetes is induced in NOD, but not NOD-scid, mice and abrogated by IL-12
    Miyaguchi, S
    Satoh, J
    Takahashi, K
    Sakata, Y
    Nakazawa, T
    Miyazaki, J
    Toyota, T
    CLINICAL IMMUNOLOGY, 2001, 98 (01) : 119 - 124
  • [35] Large-scale generation of IL-12 secreting macrophages from human pluripotent stem cells for cancer therapy
    Kang, Baoqiang
    Xing, Qi
    Huang, Yuhua
    Lin, Huaisong
    Peng, Jiaojiao
    Zhang, Zhishuai
    Wang, Mingquan
    Guo, Xinrui
    Hu, Xing
    Wang, Shuoting
    Wang, Junwei
    Gao, Minghui
    Zhu, Yanling
    Pan, Guangjin
    MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT, 2024, 32 (01)
  • [36] IL-12 delivered intratumorally by multilamellar liposomes reactivates memory T cells in human tumor microenvironments
    Simpson-Abelson, Michelle R.
    Purohit, Vivek S.
    Pang, Wing Man
    Iyer, Vandana
    Odunsi, Kunle
    Demmy, Todd L.
    Yokota, Sandra J.
    Loyall, Jenni L.
    Kelleher, Raymond J., Jr.
    Balu-Iyer, Sathy
    Bankert, Richard B.
    CLINICAL IMMUNOLOGY, 2009, 132 (01) : 71 - 82
  • [37] Identification of IL-12 induced genes in human T cells and NK cells by gene expression profiling.
    Wang, KS
    Ritz, J
    FASEB JOURNAL, 2001, 15 (04): : A348 - A348
  • [38] Identification of IL-12 induced genes in human T cells and NK cells by gene expression profiling.
    Wang, KS
    Ritz, J
    BLOOD, 2000, 96 (11) : 236A - 236A
  • [39] Safety and Efficacy of IL-12 Plasmid DNA Transfection into Pig Skin: Supportive Data for Human Clinical Trials on Gene Therapy and Vaccination
    Tratar, Ursa Lampreht
    Jesenko, Tanja
    Omerzel, Masa
    Seliskar, Alenka
    Stupan, Urban
    Djokic, Mihajlo
    Sredensek, Jerneja
    Trotovsek, Blaz
    Sersa, Gregor
    Cemazar, Maja
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (06)
  • [40] The human perforin gene is a direct target of STAT4 activated by IL-12 in NK cells
    Yamamoto, K
    Shibata, F
    Miyasaka, N
    Miura, O
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2002, 297 (05) : 1245 - 1252