On the restriction of the release of water-soluble component from polyvinyl alcohol film by blending beta-cyclodextrin

被引：0
|
作者：
Sreenivasan, K
机构：
来源：
JOURNAL OF APPLIED POLYMER SCIENCE | 1997年 / 65卷 / 09期
关键词：
D O I：
10.1002/(SICI)1097-4628(19970829)65:9<1829::AID-APP20>3.3.CO;2-E
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
The effect of adding beta-Cyclodextrin with poly(vinyl alcohol) (PVA) hydrogel on the release of a water-soluble component has been investigated. It is found that the release of a model drug, salicyclic acid, from PVA matrix in the presence of beta-cyclodextrin prolonged considerably the release of the profile of the drug from the PVA gel. The profound influence of beta-cyclodextrin on the drug release has been assigned to the ability of beta-cyclodextrin to form an inclusion complex with salicyclic acid. (C) 1997 John Wiley & Sons, Inc.
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页码：1829 / 1832
页数：4
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