Mechanisms for recovery of motor function following cortical damage

被引:232
|
作者
Nudo, Randolph J. [1 ]
机构
[1] Univ Kansas, Med Ctr, Landon Ctr Aging, Kansas City, KS 66160 USA
关键词
D O I
10.1016/j.conb.2006.10.004
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Recent studies of focal injury to the cerebral cortex have demonstrated that the remaining, intact tissue undergoes structural and functional changes that could play a substantial role in neurological recovery. New information regarding the molecular and cellular environment in the adjacent, intact tissue has suggested that waves of growth promotion and inhibition modulate the self-repair processes of the brain. Furthermore, recent studies have documented widespread neurophysiological and neuroanatomical changes in regions remote from a focal cortical injury, suggesting that entire cortical networks participate in the recovery process.
引用
收藏
页码:638 / 644
页数:7
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