Mechanisms for recovery of motor function following cortical damage

被引:232
|
作者
Nudo, Randolph J. [1 ]
机构
[1] Univ Kansas, Med Ctr, Landon Ctr Aging, Kansas City, KS 66160 USA
关键词
D O I
10.1016/j.conb.2006.10.004
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Recent studies of focal injury to the cerebral cortex have demonstrated that the remaining, intact tissue undergoes structural and functional changes that could play a substantial role in neurological recovery. New information regarding the molecular and cellular environment in the adjacent, intact tissue has suggested that waves of growth promotion and inhibition modulate the self-repair processes of the brain. Furthermore, recent studies have documented widespread neurophysiological and neuroanatomical changes in regions remote from a focal cortical injury, suggesting that entire cortical networks participate in the recovery process.
引用
收藏
页码:638 / 644
页数:7
相关论文
共 50 条
  • [1] Mechanisms of functional recovery following motor cortical lesions
    Wiesendanger, M
    Rouiller, EM
    [J]. 9TH EUROPEAN CONGRESS OF CLINICAL NEUROPHYSIOLOGY, 1998, : 343 - 348
  • [2] Recovery after damage to motor cortical areas
    Nudo, RJ
    [J]. CURRENT OPINION IN NEUROBIOLOGY, 1999, 9 (06) : 740 - 747
  • [4] Magnesium dietary manipulation and recovery of function following controlled cortical damage in the rat
    Hoane, Michael R.
    Gilbert, David R.
    Barbre, Adrianne B.
    Harrison, Stacy A.
    [J]. MAGNESIUM RESEARCH, 2008, 21 (01) : 29 - 37
  • [5] Cortical mechanisms of recovery of function after stroke
    Hallett, M
    Wassermann, EM
    Cohen, LG
    Chmielowska, J
    Gerloff, C
    [J]. NEUROREHABILITATION, 1998, 10 (02) : 131 - 142
  • [6] Recovered memory function following lateralized cortical damage
    Miller, MB
    Gazzaniga, MS
    [J]. NEOCORTICAL EPILEPSIES, 2000, 84 : 15 - 21
  • [7] Mechanisms of functional recovery following acute brain damage
    G. Berlucchi
    [J]. The Italian Journal of Neurological Sciences, 1998, 19 (Suppl 1): : S3 - S3
  • [8] Mechanisms underlying recovery of motor function after stroke
    Ward, NS
    Cohen, LG
    [J]. ARCHIVES OF NEUROLOGY, 2004, 61 (12) : 1844 - 1848
  • [9] Mechanisms underlying recovery of motor function after stroke
    Ward, NS
    [J]. POSTGRADUATE MEDICAL JOURNAL, 2005, 81 (958) : 510 - 514
  • [10] PARTIAL RECOVERY OF FORELIMB MOTOR CONTROL FOLLOWING UNILATERAL MOTOR CORTICAL ABLATION IN RATS
    PRICE, AW
    FOWLER, SC
    [J]. BULLETIN OF THE PSYCHONOMIC SOCIETY, 1977, 10 (04) : 268 - 268