Neurotransmitters and the skin. Perspectives for allergic dermatoses?

被引：2

作者：

Misery, L ^{[1
]}

Schmitt, D ^{[1
]}

Claudy, A ^{[1
]}

机构：

[1] HOP EDOUARD HERRIOT, DERMATOL CLIN, F-69437 LYON, FRANCE

来源：

REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE | 1997年 / 37卷 / 05期

关键词：

neuromediators; neuropeptides; allergy; allergic dermatoses;

D O I：

10.1016/S0335-7457(97)80050-0

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

The skin has a high density of immune cells and nerve fibers. Cutaneous neurotransmitters are very important in skin physiology and cutaneous inflammation. In the course of allergic dermatoses, such as atopic dermatitis or urticaria, the cutaneous nervous system is modified (density of nerve fibers, concentration and distribution of neuropeptides). Neurotransmitters are actively involved in the pathogenesis of the vascular and cellular phases of inflammation. These data suggest that agonists and antagonists of neurotransmitters may represent a new and very interesting alternative for the treatment of patients.

引用

页码：549 / 555

页数：7

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