Simple preparation of fluorescence probe based on CdTe quantum dots combined with MIP for selective detection of sulfadimidine

A simple fluorescence sensor for the detection of sulfadimidine (SM2) was fabricated by molecular imprinting technology. Cadmium telluride quantum dots (CdTe QDs) as the fluorescent material, 3-aminopropyltriethoxysilane (APTES) as functional monomer, sulfadimidine as template molecule and tetraethoxysilane (TEOS) as cross-linker, the CdTe QDs were embedded in silica nano-particles by reverse microemulsion method. Under optimal detection condition, response is linear in the 2-30 mu mol L-1 SM2 concentration condition with the detection limit was 0.4 mu mol L-1. In addition, the correlation coefficient was 0.9857 and the imprinting factor was 4.82. The fluorescent probe was successfully applied to the determination of SM2 in tap water and milk sample with the spiked recoveries ranging from 99.8 to 103.2%. It gets a good specific recognition ability and potential practical application value.