Titanium;
Hydroxyapatite;
Simulated body fluid;
Cladding;
IN-VITRO;
SURFACE MODIFICATION;
APATITE FORMATION;
ION IMPLANTATION;
PURE TITANIUM;
HYDROXYAPATITE;
BIOACTIVITY;
BIOCOMPATIBILITY;
REACTIVITY;
COATINGS;
D O I:
10.1016/j.msec.2009.03.021
中图分类号:
TB3 [工程材料学];
R318.08 [生物材料学];
学科分类号:
0805 ;
080501 ;
080502 ;
摘要:
To improve the bioactivity of Ti6Al4V alloy for use as a load-bearing hard tissue replacement, titanium/hydroxyapatite (Ti/HA) composites were bonded to a Ti6Al4V substrate by a novel cladding method. With the aid of a silver foil as the interlayer and an external pressure during sintering, the interfaces between the composites and the substrate were free of defects. The bioactivity of the fabricated materials was evaluated in the simulated body fluid (SBF) and the results demonstrated that the materials could induce nucleation and growth of bone-like apatite in the SBF. Factors that contributed to the bioactivity of the materials were discussed. The release of Ag+ ions from the materials was also detected, which is expected to impart antibacterial effect after implantation. and further enhance the functionalities of the materials. Crown Copyright (C) 2009 Published by Elsevier B.V. All rights reserved.
机构:
Southwest Jiaotong Univ, Tribol Res Inst, Key Lab Adv Technol Mat, Minist Educ, Chengdu 610031, Peoples R ChinaSouthwest Jiaotong Univ, Tribol Res Inst, Key Lab Adv Technol Mat, Minist Educ, Chengdu 610031, Peoples R China
Liao, Bo
Xu, Cheng
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Southwest Jiaotong Univ, Tribol Res Inst, Key Lab Adv Technol Mat, Minist Educ, Chengdu 610031, Peoples R ChinaSouthwest Jiaotong Univ, Tribol Res Inst, Key Lab Adv Technol Mat, Minist Educ, Chengdu 610031, Peoples R China
Xu, Cheng
Li, Wei
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Southwest Jiaotong Univ, Tribol Res Inst, Key Lab Adv Technol Mat, Minist Educ, Chengdu 610031, Peoples R ChinaSouthwest Jiaotong Univ, Tribol Res Inst, Key Lab Adv Technol Mat, Minist Educ, Chengdu 610031, Peoples R China
Li, Wei
Lu, Dong
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Chengdu Adv Met Mat Ind Technol Res Inst, Chengdu, Peoples R ChinaSouthwest Jiaotong Univ, Tribol Res Inst, Key Lab Adv Technol Mat, Minist Educ, Chengdu 610031, Peoples R China
Lu, Dong
Jin, Zhong Min
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Southwest Jiaotong Univ, Tribol Res Inst, Key Lab Adv Technol Mat, Minist Educ, Chengdu 610031, Peoples R ChinaSouthwest Jiaotong Univ, Tribol Res Inst, Key Lab Adv Technol Mat, Minist Educ, Chengdu 610031, Peoples R China
机构:
Washington State Univ, Sch Mech & Mat Engn, W M Keck Biomed Mat Res Lab, Pullman, WA 99164 USAWashington State Univ, Sch Mech & Mat Engn, W M Keck Biomed Mat Res Lab, Pullman, WA 99164 USA
Ciliveri, Sushant
Bandyopadhyay, Amit
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Washington State Univ, Sch Mech & Mat Engn, W M Keck Biomed Mat Res Lab, Pullman, WA 99164 USAWashington State Univ, Sch Mech & Mat Engn, W M Keck Biomed Mat Res Lab, Pullman, WA 99164 USA