Label-free dual assay of DNA sequences and potassium ions using an aptamer probe and a molecular light switch complex

被引：66

作者：

Choi, Min Sun ^{[1
]}

Yoon, Minji ^{[1
]}

Baeg, Jin-Ook ^{[2
]}

Kim, Jinheung ^{[1
]}

机构：

[1] Ewha Womans Univ, Dept Chem & Nano Sci, Seoul 120750, South Korea

[2] Korea Res Inst Chem Technol, Adv Chem Technol Div, Taejon 305343, South Korea

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 47期

关键词：

BINDING; RUTHENIUM(II); FLUORESCENCE; QUADRUPLEXES; POLYMER; WATER;

D O I：

10.1039/b915994k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A homogeneous assay is reported using Ru(phen)(2)(dppz)(2+) and a K+-binding aptamer for the selective and sensitive detection of a target oligonucleotide and potassium ions, based on reduction in fluorescence emission according to the formation of the G-quadruplex structure from the aptamer in the presence of K+.

引用

页码：7419 / 7421

页数：3

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