Synthesis and spectral properties of 2-methylthio-3H-7-[(o-; m- and p-substituted)phenoxy]-4-(p-substituted-phenyl)-[1,5]benzodiazepines

series of eleven new 2-methylthio-3H-7-[(o-; m- and p-substituted) phenoxy]-4-(p-substituted-phenyl)-[1,5]benzodiazepines, which have potentially useful pharmacological activities, has been synthesized by condensing the 4-[(o-; m- and p-R(1))phenoxyl-1,2-phenylendiamines with 3,3-dimercapto-1-(p-R(2)-phenyl)-2-propen-1-one. Afterward the 1H-[1,5]benzodiazepine-2-thiones obtained were treated with sodium hydride and methyl iodide. The structure of all products was corroborated by ir, (1)H nmr, (13)C nmr and ms.