FORMAL TOTAL SYNTHESIS OF (±)-STRICTAMINE

被引:6
|
作者
Sato, Keigo [1 ]
Takanashi, Noriyuki [1 ]
Kogure, Noriyuki [1 ]
Kitajima, Mariko [1 ]
Takayama, Hiromitsu [1 ]
机构
[1] Chiba Univ, Grad Sch Pharmaceut Sci, Lab Biofunct Mol Chem, Chuo Ku, 1-8-1 Inohana, Chiba 2608675, Japan
基金
日本学术振兴会;
关键词
ASYMMETRIC TOTAL-SYNTHESIS; AKUAMMILINE ALKALOIDS; INDOLE ALKALOIDS; STRICTAMINE; ECHITAMINE; CONSTRUCTION; REARRANGEMENT; SCHOLARISINE; CYCLIZATION; FRAMEWORK;
D O I
10.3987/COM-18-S(T)24
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A formal total synthesis of an alcuammiline-type indole alkaloid, (+/-)-strictamine, which features ozonolysis, the Staudinger reaction, and the aza-Wittig reaction to construct its D-ring, is reported.
引用
收藏
页码:365 / 382
页数:18
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