REM sleep disruption and periodic breathing are common in hypoxic environments, such as at altitude (7). Periodic breathing does not occur often in intact unanesthetized cats as a hypoxic ventilatory response, but occurs frequently as a post-hypoxic response (3, 5). Our recordings of medullary respiratory neurons and diaphragmatic activity indicate that periodic breathing results from central changes in levels of phasic and tonic respiratory output. Experimental studies in cat indicate that hypocapnia causes REM sleep disruption and therefore that it, rather than hypoxia, may be responsible for the sleep disruption at altitude.
机构:
Wenzhou Med Univ, Cixi Biomed Res Inst, Ningbo, Peoples R ChinaWenzhou Med Univ, Cixi Biomed Res Inst, Ningbo, Peoples R China
Hu, Fei
Yu, Yicong
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机构:
Zhejiang Ctr Anim Dis Control, Hangzhou, Peoples R ChinaWenzhou Med Univ, Cixi Biomed Res Inst, Ningbo, Peoples R China
Yu, Yicong
Xu, Hongming
论文数: 0引用数: 0
h-index: 0
机构:
Wenzhou Med Univ, Affiliated Cixi Hosp, Dept Orthopaed Surg, 999 South Second Ring Rd, Ningbo 315300, Zhejiang, Peoples R ChinaWenzhou Med Univ, Cixi Biomed Res Inst, Ningbo, Peoples R China
Xu, Hongming
HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM,
2024,
23
(03):
: 385
-
393
机构:
Univ New South Wales, Sch Biotechnol & Biomol Sci, Sydney, NSW 2052, Australia
Univ Virginia, Dept Pharmacol, Charlottesville, VA 22908 USAUniv New South Wales, Sch Biotechnol & Biomol Sci, Sydney, NSW 2052, Australia
机构:
UT Southwestern Med Ctr, Dept Radiol, 5323 Harry Hines Blvd, Dallas, TX 75390 USAUT Southwestern Med Ctr, Dept Radiol, 5323 Harry Hines Blvd, Dallas, TX 75390 USA