1-[(ARYL)(4-ARYL-1H-PYRROL-3-YL)METHYL]-1H-IMIDAZOLES ARE NOVEL ANTI-TRYPANOSOMA CRUZI AGENTS

被引:0
|
作者
Di Santo, Roberto [1 ]
Iacovo, Alberto [1 ]
Miele, Gaetano [1 ]
Crucitti, Giuliana Cuzzucoli [1 ]
Rosi, Federica [1 ]
Pepe, Valentina [1 ]
Verlinde, Christophe [2 ,3 ]
Gelb, Michael [4 ]
Costi, Roberta [1 ]
机构
[1] Univ Roma La Sapienza, Dipartimento Chim & Tecnol Farmaco, Rome, Italy
[2] Univ Washington, Dept Biochem, Biomol Struct Ctr, Seattle, WA 98195 USA
[3] Univ Washington, Dept Biol Struct, Biomol Struct Ctr, Seattle, WA 98195 USA
[4] Univ Washington, Dept Chem, Seattle, WA 98195 USA
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:129 / 129
页数:1
相关论文
共 50 条
  • [21] One-pot, four-component synthesis of novel cytotoxic agents 1-(5-aryl-1,3,4-oxadiazol-2-y1)-1-(1H-pyrrol-2-yl)methanamines
    Ramazani, Ali
    Khoobi, Mehdi
    Torkaman, Azar
    Nasrabadi, Fatemeh Zeinali
    Forootanfar, Hamid
    Shakibaie, Mojtaba
    Jafari, Mandana
    Ameri, Alieh
    Emami, Saeed
    Faramarzi, Mohammad Ali
    Foroumadi, Alireza
    Shafiee, Abbas
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 78 : 151 - 156
  • [22] Synthesis and antimicrobial screening of some 3-[4-(3-aryl-1-phenyl-1H-pyrazol-4-yl)-6-aryl-pyridin-2-yl] and 4-methyl-3-phenyl-6-[4-(3-aryl-1-phenyl-1H-pyrazol-4-yl)-6-aryl-pyridin-2-yl] coumarins
    Brahmbhatt, D. I.
    Kaneria, Ankit R.
    Patel, Anil K.
    Patel, Niraj H.
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2010, 49 (07): : 971 - 977
  • [23] Thermochemical properties of different 1-(R-phenyl)-1H-imidazoles
    Emel'yanenko, Vladimir N.
    Kaliner, Maria
    Strassner, Thomas
    Verevkin, Sergey P.
    FLUID PHASE EQUILIBRIA, 2017, 433 : 40 - 49
  • [24] Synthesis of 5-[1-Aryl-pyrrol-2-yl]-1H-tetrazole
    Liu, Wei
    Ma, Yuan
    Yin, Ying-Wu
    Zhao, Yu-Fen
    Gaodeng Xuexiao Huaxue Xuebao/Chemical Journal of Chinese Universities, 2006, 27 (08): : 1472 - 1475
  • [25] Synthesis and biological evaluation of aryl 1,2,4-oxadiazole incorporated (2-(oxazol)-1H-imidazoles as anticancer agents
    Bairi, Suresh
    Alagarsamy, Veerachamy
    Rachamalla, Shyam Sunder
    Eppakayala, Laxminarayana
    RESULTS IN CHEMISTRY, 2022, 4
  • [26] Synthesis of 5-[1-aryl-pyrrol-2-yl]-1H-tetrazole
    Liu Wei
    Ma Yuan
    Yin Ying-Wu
    Zhao Yu-Fen
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2006, 27 (08): : 1472 - 1475
  • [27] ANTIFUNGAL AGENTS .2. SYNTHESIS AND ANTIFUNGAL ACTIVITIES OF ARYL-1H-PYRROL-2-YL-1H-IMIDAZOL-1-YL-METHANE DERIVATIVES WITH UNSATURATED CHAINS
    MASSA, S
    RAGNO, R
    PORRETTA, GC
    MAI, A
    RETICO, A
    ARTICO, M
    SIMONETTI, N
    ARCHIV DER PHARMAZIE, 1993, 326 (09) : 539 - 546
  • [28] SYNTHESIS AND OPTICAL STUDIES OF 2,4,5-TRI[2-(ARYL)-ETHENYL]-1H-IMIDAZOLES
    Babar, Rabia
    Munawar, Munawar Ali
    HETEROCYCLES, 2019, 98 (03) : 429 - 436
  • [29] Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents
    dos Santos Filho, Jose Mauricio
    Lima Leite, Ana Cristina
    de Oliveira, Boaz Galdino
    Magalhaes Moreira, Diogo Rodrigo
    Lima, Milena S.
    Pereira Soares, Milena Botelho
    Leite, Lucia Fernanda C. C.
    BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 17 (18) : 6682 - 6691
  • [30] Studies on isocyanides and related compounds. Synthesis of 1-aryl-2-(tosylamino)-1H-imidazoles, a novel class of imidazole derivatives
    Bossio, R
    Marcaccini, S
    Pepino, R
    JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (06): : 2202 - 2203