Patients with giant congenital melanocytic naevi (GCMN) have an increased risk for developing melanoma including both cutaneous and extracutaneous melanoma. Till now there is no scientific evidence that therapeutic interventions alter the overall malignancy risk in an important way. This article discusses the rationale for treatment, our long-term experience in the management of these patients and shows evidence that curettage might be of benefit in the prevention of cutaneous melanoma.
机构:
Karolinska Inst, Dept Med Solna, Dermatol & Venereol Unit, SE-17176 Stockholm, SwedenKarolinska Inst, Dept Med Solna, Dermatol & Venereol Unit, SE-17176 Stockholm, Sweden
Drakensjo, Iara Trocoli
Hedblad, Mari-Anne
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机构:Karolinska Inst, Dept Med Solna, Dermatol & Venereol Unit, SE-17176 Stockholm, Sweden
Hedblad, Mari-Anne
Wahlgren, Carl-Fredrik
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机构:Karolinska Inst, Dept Med Solna, Dermatol & Venereol Unit, SE-17176 Stockholm, Sweden